C4B63_13g189

ubiquitin-like protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100933 OG7: OG7_0004831 171 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 171 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_42g242 ⚠
2-hydroxy-3-oxopropionate reductase
— OG7
C4B63_12g21 ⚠
Uncharacterized oxidoreductase YkwC
— OG7
C4B63_6g269 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_60g80 ⚠
dihydroorotase
— OG7
C4B63_4g146 ⚠
pyruvate kinase 2
— OG7
C4B63_227g20 ⚠
pyruvate kinase 2
— OG7
C4B63_171g22 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_93g62 ⚠
Pentatricopeptide repeat-containing protein
— OG7
C4B63_47g40 ⚠
CS domain containing protein
— OG7
C4B63_242g2 ⚠
protein kinase
— OG7
C4B63_6g395 ⚠
Elongation factor G 2, mitochondrial
— OG7
C4B63_4g226 ⚠
UTP-glucose-1-phosphate uridylyltransferase 2
— OG7
C4B63_58g54 ⚠
serine/threonine protein kinase
— OG7
C4B63_89g43 ⚠
PITH domain-containing protein
— OG7
C4B63_79g87 ⚠
phosphoglucomutase
— OG7
C4B63_2g235 ⚠
Co-chaperone protein P23
— OG7
C4B63_13g230 ⚠
Eukaryotic translation initiation factor 6
— OG7
C4B63_7g133 ⚠
pyroglutamyl-peptidase I
— OG7
C4B63_6g234 ⚠
Elongation factor G 2, mitochondrial
— OG7
C4B63_19g185 ⚠
isocitrate dehydrogenase
— OG7
C4B63_4g180 ⚠
serine/threonine protein kinase
— OG7
C4B63_11g29 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG7
C4B63_45g139 ⚠
serine/threonine protein kinase
— OG7
C4B63_282g13 ⚠
Elongation factor G 2, mitochondrial
— OG7
C4B63_43g124 ⚠
RNA polymerase II
— OG7
C4B63_39g342 ⚠
phosphoenolpyruvate mutase
— OG7
C4B63_267g13 ⚠
Nuclear protein localization protein 4 homolo
— OG7
C4B63_4g577 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_78g19 ⚠
conserved hypothetical protein
— OG7
C4B63_52g143 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— OG7
C4B63_42g205 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_134g36 ⚠
dihydroorotase
— OG7
C4B63_58g37 ⚠
conserved hypothetical protein
— OG7
C4B63_39g311 ⚠
conserved hypothetical protein
— OG7
C4B63_12g315 ⚠
Nuclear protein localization protein 4 homolo
— OG7
C4B63_23g122 ⚠
serine/threonine protein kinase
— OG7
C4B63_35g129 ⚠
dihydroorotase
— OG7
C4B63_40g25 ⚠
Biotin--acetyl-CoA-carboxylase ligase
— OG7
C4B63_42g204 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_2g551 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
C4B63_13g231 ⚠
serine/threonine protein kinase
— OG7
C4B63_10g488 ⚠
UBX domain-containing protein
— OG7
C4B63_90g47 ⚠
UPF0652 protein
— OG7
C4B63_2g177 ⚠
UPF0652 protein
— OG7
C4B63_227g9 ⚠
mevalonate-diphosphate decarboxylase
— OG7
C4B63_92g63 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
C4B63_208g34 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
C4B63_69g28 ⚠
UBA/TS-N domain/CUE domain/Domain of unknown
— OG7
C4B63_55g69 ⚠
conserved hypothetical protein
— OG7
C4B63_8g539 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.