C4B63_282g13

Elongation factor G 2, mitochondrial
Trypanosoma cruzi Dm28c 2018 OG6: OG6_103657 OG7: OG7_0003018 167 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 167 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_83g29 ⚠
ATP-dependent protease ATPase subunit HslU1
— OG7
C4B63_27g229 ⚠
cyclin 1
— OG7
C4B63_9g488 ⚠
conserved hypothetical protein
— OG7
C4B63_7g361 ⚠
phosphomannomutase-like protein
— OG7
C4B63_35g125 ⚠
transaldolase
— OG7
C4B63_4g146 ⚠
pyruvate kinase 2
— OG7
C4B63_227g20 ⚠
pyruvate kinase 2
— OG7
C4B63_2g94 ⚠
conserved hypothetical protein
— OG7
C4B63_48g23 ⚠
nicotinate phosphoribosyltransferase
— OG7
C4B63_89g43 ⚠
PITH domain-containing protein
— OG7
C4B63_112g33 ⚠
haloacid dehalogenase hydrolase
— OG7
C4B63_253g15 ⚠
haloacid dehalogenase-like hydrolase
— OG7
C4B63_6g146 ⚠
haloacid dehalogenase-like hydrolase
— OG7
C4B63_30g112 ⚠
haloacid dehalogenase hydrolase
— OG7
C4B63_6g148 ⚠
haloacid dehalogenase-like hydrolase
— OG7
C4B63_90g47 ⚠
UPF0652 protein
— OG7
C4B63_2g177 ⚠
UPF0652 protein
— OG7
C4B63_48g116 ⚠
5'-3' exoribonuclease D
— OG7
C4B63_25g220 ⚠
5'-3' exoribonuclease B
— OG7
C4B63_6g572 ⚠
5'-3' exoribonuclease A
— OG7
C4B63_42g174 ⚠
conserved hypothetical protein
— OG7
C4B63_14g188 ⚠
UPF0769 protein C21orf59 homolog B
— OG7
C4B63_55g26 ⚠
conserved hypothetical protein
— OG7
C4B63_238g18 ⚠
GMP synthase(fragment)
— OG7
C4B63_142g6 ⚠
GMP synthase
— OG7
C4B63_4g357 ⚠
Activator of 90 kDa heat shock protein ATPase
— OG7
C4B63_14g183 ⚠
mitochondrial intermediate peptidase
— OG7
C4B63_42g62 ⚠
dTDP-glucose 4,6-dehydratase
— OG7
C4B63_6g385 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
C4B63_56g64 ⚠
Present in the outer mitochondrial membrane p
— OG7
C4B63_7g332 ⚠
adenosine kinase
— OG7
C4B63_37g366 ⚠
thimet oligopeptidase
— OG7
C4B63_19g259 ⚠
conserved hypothetical protein
— OG7
C4B63_13g189 ⚠
ubiquitin-like protein
— OG7
C4B63_42g63 ⚠
adenosine kinase
— OG7
C4B63_62g82 ⚠
thimet oligopeptidase
— OG7
C4B63_230g26 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
C4B63_42g67 ⚠
Protein F37C4.5
— OG7
C4B63_243g4 ⚠
Present in the outer mitochondrial membrane p
— OG7
C4B63_24g191 ⚠
deoxyhypusine hydroxylase
— OG7
C4B63_23g269 ⚠
conserved hypothetical protein
— OG7
C4B63_27g180 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
C4B63_42g205 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_28g64 ⚠
aspartate aminotransferase
— OG7
C4B63_2g551 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
C4B63_42g204 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_129g42 ⚠
diphthine synthase
— OG7
C4B63_140g30 ⚠
diphthine synthase
— OG7
C4B63_4g577 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_4g136 ⚠
N-myristoyl transferase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.