C4B63_4g577

eukaryotic translation initiation factor 4E (eIF4E) interacting protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101698 OG7: OG7_0002303 249 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 249 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_224g16 ⚠
conserved hypothetical protein
— OG7
C4B63_12g300 ⚠
TAP42-like family
— OG7
C4B63_4g137 ⚠
N-myristoyl transferase
— OG7
C4B63_22g64 ⚠
Poly(A) RNA polymerase GLD2-A
— OG7
C4B63_10g437 ⚠
U-box domain protein
— OG7
C4B63_21g261 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG7
C4B63_2g566 ⚠
phenylalanyl-tRNA synthetase
— OG7
C4B63_9g331 ⚠
transcription elongation factor s-II
— OG7
C4B63_28g48 ⚠
transcription elongation factor
— OG7
C4B63_82g92 ⚠
conserved hypothetical protein
— OG7
C4B63_63g46 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— OG7
C4B63_77g26 ⚠
conserved hypothetical protein
— OG7
C4B63_49g685c ⚠
small nuclear ribonucleoprotein
— OG7
C4B63_114g20 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic
— OG7
C4B63_8g539 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic
— OG7
C4B63_84g49 ⚠
RNA-binding protein
— OG7
C4B63_92g63 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
C4B63_69g28 ⚠
UBA/TS-N domain/CUE domain/Domain of unknown
— OG7
C4B63_208g34 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
C4B63_16g19 ⚠
5'-3' exoribonuclease C
— OG7
C4B63_1g73 ⚠
conserved hypothetical protein
— OG7
C4B63_162g37 ⚠
mitochondrial DNA polymerase I protein D
— OG7
C4B63_46g13 ⚠
mitochondrial DNA polymerase I protein D
— OG7
C4B63_5g416 ⚠
conserved hypothetical protein
— OG7
C4B63_51g200 ⚠
mitochondrial DNA polymerase I protein B
— OG7
C4B63_55g69 ⚠
conserved hypothetical protein
— OG7
C4B63_55g68 ⚠
conserved hypothetical protein
— OG7
C4B63_6g257 ⚠
Vacuolar proton pump subunit B
— OG7
C4B63_6g258 ⚠
Vacuolar proton pump subunit B
— OG7
C4B63_12g211 ⚠
conserved hypothetical protein
— OG7
C4B63_12g212 ⚠
conserved hypothetical protein
— OG7
C4B63_41g128 ⚠
conserved hypothetical protein
— OG7
C4B63_6g385 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
C4B63_6g572 ⚠
5'-3' exoribonuclease A
— OG7
C4B63_40g163 ⚠
leucine-rich repeat protein (LRRP)
— OG7
C4B63_17g50 ⚠
Outer row dynein-assembly protein 7
— OG7
C4B63_8g58 ⚠
Dynein assembly factor 1, axonemal homolog
— OG7
C4B63_6g400 ⚠
conserved hypothetical protein
— OG7
C4B63_282g21 ⚠
conserved hypothetical protein
— OG7
C4B63_42g174 ⚠
conserved hypothetical protein
— OG7
C4B63_57g94 ⚠
ATP-dependent RNA helicase
— OG7
C4B63_23g275 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_23g186 ⚠
aspartyl aminopeptidase
— OG7
C4B63_14g188 ⚠
UPF0769 protein C21orf59 homolog B
— OG7
C4B63_55g26 ⚠
conserved hypothetical protein
— OG7
C4B63_238g18 ⚠
GMP synthase(fragment)
— OG7
C4B63_142g6 ⚠
GMP synthase
— OG7
C4B63_142g11 ⚠
Protein shuttle craft
— OG7
C4B63_24g191 ⚠
deoxyhypusine hydroxylase
— OG7
C4B63_23g269 ⚠
conserved hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.