C4B63_23g275

ATP-dependent DEAD/H RNA helicase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_105684 OG7: OG7_0002665 181 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 181 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_63g41 ⚠
replication factor C, subunit 3
— OG7
C4B63_173g6 ⚠
Soluble NSF attachment protein, SNAP (parafla
— Both
C4B63_34g375 ⚠
Soluble NSF attachment protein, SNAP (parafla
— Both
C4B63_70g80 ⚠
proteasome alpha 7 subunit
— +1 more Both
C4B63_17g179 ⚠
Importin subunit beta-3
— OG7
C4B63_20g226 ⚠
Probable importin subunit beta-4
— OG7
C4B63_22g51 ⚠
conserved hypothetical protein
— OG7
C4B63_33g145 ⚠
methyltransferase
— OG7
C4B63_29g183 ⚠
methyltransferase
— OG7
C4B63_16g331 ⚠
ubiquitin-activating enzyme E1
— OG7
C4B63_13g152 ⚠
elongation factor 2
— OG7
C4B63_2g786 ⚠
ubiquitin-activating enzyme E1
— OG7
C4B63_13g157 ⚠
elongation factor 2
— OG7
C4B63_13g153 ⚠
elongation factor 2
— OG7
C4B63_160g33 ⚠
ubiquitin-activating enzyme E1
— OG7
C4B63_11g18 ⚠
translation elongation factor EF-2
— OG7
C4B63_11g17 ⚠
translation elongation factor EF-2
— OG7
C4B63_13g156 ⚠
elongation factor 2
— OG7
C4B63_9g523 ⚠
U5 small nuclear ribonucleoprotein component
— OG7
C4B63_13g155 ⚠
elongation factor 2
— OG7
C4B63_13g154 ⚠
elongation factor 2
— OG7
C4B63_2g70 ⚠
conserved hypothetical protein
— OG7
C4B63_43g129 ⚠
proteasome subunit alpha type-5
— OG7
C4B63_25g312 ⚠
proteasome alpha 3 subunit
— OG7
C4B63_48g135 ⚠
proteasome subunit alpha type-1
— OG7
C4B63_48g131 ⚠
proteasome subunit beta type-5
— OG7
C4B63_31g109 ⚠
ribose-phosphate pyrophosphokinase
— OG7
C4B63_2g823 ⚠
acyl-CoA dehydrogenase
— OG7
C4B63_113g52 ⚠
conserved hypothetical protein
— OG7
C4B63_157g19 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_7g235 ⚠
Carboxypeptidase-like protein
— OG7
C4B63_40g50 ⚠
metallo-peptidase, Clan MC, Family M14
— OG7
C4B63_17g50 ⚠
Outer row dynein-assembly protein 7
— OG7
C4B63_359g9 ⚠
conserved hypothetical protein
— OG7
C4B63_78g13 ⚠
Proteasome activator complex subunit 4
— OG7
C4B63_171g22 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_113g49 ⚠
metallo-peptidase, Clan MC, Family M14
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_61g81 ⚠
conserved hypothetical protein
— OG7
C4B63_6g252 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_14g68 ⚠
paraflagellar rod component
— OG7
C4B63_2g450 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_78g9 ⚠
conserved hypothetical protein
— OG7
C4B63_2g815 ⚠
conserved hypothetical protein
— OG7
C4B63_488g7 ⚠
conserved hypothetical protein
— OG7
C4B63_234g11 ⚠
conserved hypothetical protein
— OG7
C4B63_24g301 ⚠
phosphatidylinositol-4-phosphate 5-kinase
— OG7
C4B63_249g17 ⚠
conserved hypothetical protein
— OG7
C4B63_78g11 ⚠
conserved hypothetical protein
— OG7
C4B63_359g17 ⚠
conserved hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.