C4B63_42g174

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_146793 OG7: OG7_0037550 228 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 228 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_16g163
Pyridoxal phosphate homeostasis protein
— Both
C4B63_29g3 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— OG7
C4B63_33g8 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— OG7
C4B63_46g15 ⚠
Kinesin-13 5
— OG7
C4B63_325g1 ⚠
Kinesin-13 1
— OG7
C4B63_69g61 ⚠
Kinesin-13 1
— OG7
C4B63_44g235 ⚠
Kinesin-13 4
— OG7
C4B63_144g30 ⚠
Kinesin-13 1
— OG7
C4B63_1g57
AAA ATPase
— Both
C4B63_9g331 ⚠
transcription elongation factor s-II
— Both
C4B63_186g7 ⚠
cleavage and polyadenylation specificity fact
— Both
C4B63_18g325 ⚠
endosomal trafficking protein RME-8
— Both
C4B63_13g243
intraflagellar transport protein 122B(fragmen
— Both
C4B63_127g30 ⚠
Flagellum attachment zone protein 14
— Both
C4B63_63g98
ubiquitin-protein ligase
— OG6
C4B63_278g6 ⚠
endosomal trafficking protein RME-8
— Both
C4B63_4g103
intraflagellar transport protein 140
— Both
C4B63_4g242 ⚠
protein kinase A catalytic subunit 3
— OG6
C4B63_42g168
CDC16
— Both
C4B63_2g156 ⚠
protein kinase A catalytic subunit 3
— OG6
C4B63_17g128 ⚠
cleavage and polyadenylation specificity fact
— Both
C4B63_279g8 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_44g252 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_41g200 ⚠
Anaphase-promoting complex subunit 8
— Both
C4B63_163g31 ⚠
conserved hypothetical protein
— Both
C4B63_30g273 ⚠
conserved hypothetical protein
— Both
C4B63_230g26 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
C4B63_6g385 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
C4B63_114g23
UBX domain-containing protein 3
— Both
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— Both
C4B63_45g69 ⚠
Dynein heavy chain 1, axonemal
— OG6
C4B63_38g151 ⚠
tetratricopeptide repeat protein (TPR)
— Both
C4B63_38g152 ⚠
tetratricopeptide repeat protein (TPR)
— Both
C4B63_6g572 ⚠
5'-3' exoribonuclease A
— Both
C4B63_3g494 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_3g241 ⚠
mucin TcMUC
— OG6
C4B63_48g116 ⚠
5'-3' exoribonuclease D
— Both
C4B63_3g686 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_125g66 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_8g545
conserved hypothetical protein
— Both
C4B63_23g242 ⚠
radial spoke protein RSP10
— Both
C4B63_128g60
zinc-finger protein family member
— Both
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— Both
C4B63_42g254
conserved hypothetical protein
— Both
C4B63_6g146 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_28g64 ⚠
aspartate aminotransferase
— Both
C4B63_6g148 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_54g69 ⚠
aspartate aminotransferase
— Both
C4B63_30g144
Cilia- and flagella-associated protein 52
— Both
C4B63_30g145
electron-transfer-flavoprotein, alpha polypep
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.