C4B63_2g156

protein kinase A catalytic subunit 3
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100326 OG7: OG7_0000103 57 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 57 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_30g273 ⚠
conserved hypothetical protein
— OG6
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— OG6
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG6
C4B63_22g113 ⚠
phosphatidylinositol 3-kinase
— OG6
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— OG6
C4B63_49g186 ⚠
ccr4-not transcription complex subunit
— OG6
C4B63_4g481 ⚠
Flagellum attachment zone protein 7
— OG6
C4B63_4g480 ⚠
Flagellum attachment zone protein 7(fragment)
— OG6
C4B63_18g212 ⚠
valyl-tRNA synthetase
— OG6
C4B63_42g254 ⚠
conserved hypothetical protein
— OG6
C4B63_4g103 ⚠
intraflagellar transport protein 140
— OG6
C4B63_278g6 ⚠
endosomal trafficking protein RME-8
— OG6
C4B63_18g325 ⚠
endosomal trafficking protein RME-8
— OG6
C4B63_63g98 ⚠
ubiquitin-protein ligase
— OG6
C4B63_13g243 ⚠
intraflagellar transport protein 122B(fragmen
— OG6
C4B63_128g60 ⚠
zinc-finger protein family member
— OG6
C4B63_163g31 ⚠
conserved hypothetical protein
— OG6
C4B63_23g240 ⚠
Eukaryotic translation initiation factor 2 su
— OG6
C4B63_41g200 ⚠
Anaphase-promoting complex subunit 8
— OG6
C4B63_42g174 ⚠
conserved hypothetical protein
— OG6
C4B63_42g168 ⚠
CDC16
— OG6
C4B63_1g57 ⚠
AAA ATPase
— OG6
C4B63_127g30 ⚠
Flagellum attachment zone protein 14
— OG6
C4B63_11g472 ⚠
chaperone DNAJ protein
— OG6
C4B63_6g493 ⚠
serine/threonine-protein phosphatase PP1
— OG6
C4B63_249g24 ⚠
serine/threonine-protein phosphatase PP1
— OG6
C4B63_326g17 ⚠
serine/threonine-protein phosphatase PP1
— OG6
C4B63_104g47 ⚠
serine/threonine-protein phosphatase PP1
— OG6
C4B63_358g2 ⚠
serine/threonine-protein phosphatase PP1
— OG6
C4B63_220g9 ⚠
conserved hypothetical protein
— OG6
C4B63_175g16 ⚠
Pre-mRNA-processing factor 19
— OG6
C4B63_43g187 ⚠
structural maintenance of chromosome protein
— OG6
C4B63_87g21 ⚠
conserved hypothetical protein
— OG6
C4B63_87g20 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG6
C4B63_56g95 ⚠
paraflagellar rod protein
— OG6
C4B63_4g513 ⚠
Target of rapamycin complex subunit LST8
— OG6
C4B63_7g316 ⚠
ruvB-like DNA helicase
— OG6
C4B63_263g7 ⚠
ruvB-like DNA helicase
— OG6
C4B63_45g234 ⚠
ubiquitin-protein ligase-like
— OG6
C4B63_45g236 ⚠
ubiquitin-protein ligase
— OG6
C4B63_45g232 ⚠
ubiquitin-protein ligase-like
— OG6
C4B63_45g235 ⚠
ubiquitin-protein ligase-like
— OG6
C4B63_43g141 ⚠
conserved hypothetical protein
— OG6
C4B63_42g593c ⚠
small nuclear ribonucleoprotein Sm-E
— OG6
C4B63_149g16 ⚠
conserved hypothetical protein
— OG6
C4B63_45g71 ⚠
conserved hypothetical protein
— OG6
C4B63_45g70 ⚠
conserved hypothetical protein
— OG6
C4B63_45g69 ⚠
Dynein heavy chain 1, axonemal
— OG6
C4B63_38g151 ⚠
tetratricopeptide repeat protein (TPR)
— OG6
C4B63_38g152 ⚠
tetratricopeptide repeat protein (TPR)
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.