C4B63_175g16

Pre-mRNA-processing factor 19
Trypanosoma cruzi Dm28c 2018 OG6: OG6_102145 OG7: OG7_0007160 128 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 128 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_14g219
Pre-mRNA-splicing factor prp5
— Both
C4B63_7g55 ⚠
conserved hypothetical protein
— OG7
C4B63_4g534
conserved hypothetical protein
— Both
C4B63_43g2 ⚠
kinesin
— Both
C4B63_168g33 ⚠
kinesin
— Both
C4B63_43g1 ⚠
kinesin
— Both
C4B63_43g3 ⚠
kinesin
— Both
C4B63_102g81 ⚠
kinesin
— Both
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— Both
C4B63_45g228
conserved hypothetical protein
— Both
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— Both
C4B63_22g113 ⚠
phosphatidylinositol 3-kinase
— Both
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— Both
C4B63_9g247
small nuclear ribonucleoprotein protein
— Both
C4B63_49g186
ccr4-not transcription complex subunit
— Both
C4B63_4g481 ⚠
Flagellum attachment zone protein 7
— OG6
C4B63_4g480 ⚠
Flagellum attachment zone protein 7(fragment)
— OG6
C4B63_58g110
conserved hypothetical protein
— Both
C4B63_30g273 ⚠
conserved hypothetical protein
— Both
C4B63_163g31 ⚠
conserved hypothetical protein
— Both
C4B63_41g200 ⚠
Anaphase-promoting complex subunit 8
— Both
C4B63_179g2 ⚠
2-oxoglutarate dehydrogenase subunit
— Both
C4B63_179g1 ⚠
2-oxoglutarate dehydrogenase E1 component(fra
— Both
C4B63_19g275 ⚠
2-oxoglutarate dehydrogenase subunit
— Both
C4B63_11g281 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_40g18 ⚠
2-oxoglutarate dehydrogenase E1 component
— Both
C4B63_1g57
AAA ATPase
— Both
C4B63_11g52
conserved hypothetical protein
— OG7
C4B63_33g8 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— OG7
C4B63_29g3 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— OG7
C4B63_56g104 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— OG7
C4B63_81g15 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_7g56 ⚠
Protein transport protein sec71
— OG7
C4B63_63g101 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
C4B63_2g729 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
C4B63_31g46 ⚠
structural maintenance of chromosome 3 protei
— OG7
C4B63_14g249 ⚠
structural maintenance of chromosome 3
— OG7
C4B63_11g283c ⚠
U6 snRNA-associated Sm-like protein LSm8
— OG7
C4B63_43g1065c ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
C4B63_17g180c
U6 snRNA-associated Sm-like protein LSm4
— OG7
C4B63_271g80c ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
C4B63_69g174c ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
C4B63_144g102c ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
C4B63_61g104
conserved hypothetical protein
— OG7
C4B63_17g277 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_17g278 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_7g424 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— OG7
C4B63_127g31 ⚠
Flagellum attachment zone protein 14
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.