C4B63_56g104

Phosphatidylinositol 4-phosphate 5-kinase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_103378 OG7: OG7_0007400 149 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 149 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_10g450 ⚠
flagellar radial spoke protein-like
— OG7
C4B63_51g174 ⚠
Flagellar radial spoke protein 4/6
— Both
C4B63_42g254 ⚠
conserved hypothetical protein
— OG7
C4B63_10g290 ⚠
Paraflagellar rod protein 2
— OG7
C4B63_528g4 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
C4B63_7g392 ⚠
ubiquitin hydrolase
— OG7
C4B63_2g502 ⚠
ubiquitin carboxyl-terminal hydrolase
— OG7
C4B63_252g9 ⚠
ubiquitin carboxyl-terminal hydrolase
— OG7
C4B63_233g32 ⚠
ubiquitin hydrolase
— OG7
C4B63_233g31 ⚠
ubiquitin hydrolase
— OG7
C4B63_4g502 ⚠
ABC transporter
— OG7
C4B63_23g223 ⚠
cyclic nucleotide phosphodiesterase
— OG7
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_42g168 ⚠
CDC16
— OG7
C4B63_38g151 ⚠
tetratricopeptide repeat protein (TPR)
— OG7
C4B63_18g314 ⚠
conserved hypothetical protein
— OG7
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— OG7
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_56g95 ⚠
paraflagellar rod protein
— OG7
C4B63_1g32 ⚠
conserved hypothetical protein
— OG7
C4B63_7g424 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_7g377 ⚠
[Pyruvate dehydrogenase (acetyl-transferring)
— OG7
C4B63_81g14 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_30g273 ⚠
conserved hypothetical protein
— OG7
C4B63_7g55 ⚠
conserved hypothetical protein
— OG7
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_87g21 ⚠
conserved hypothetical protein
— OG7
C4B63_7g57 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_43g187 ⚠
structural maintenance of chromosome protein
— OG7
C4B63_220g9 ⚠
conserved hypothetical protein
— OG7
C4B63_87g20 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_28g25 ⚠
pyruvate dehydrogenase (lipoamide) kinase
— OG7
C4B63_38g152 ⚠
tetratricopeptide repeat protein (TPR)
— OG7
C4B63_128g60 ⚠
zinc-finger protein family member
— OG7
C4B63_235g8 ⚠
conserved hypothetical protein
— OG7
C4B63_63g101 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
C4B63_127g31 ⚠
Flagellum attachment zone protein 14
— OG7
C4B63_14g249 ⚠
structural maintenance of chromosome 3
— OG7
C4B63_41g200 ⚠
Anaphase-promoting complex subunit 8
— OG7
C4B63_1g57 ⚠
AAA ATPase
— OG7
C4B63_43g141 ⚠
conserved hypothetical protein
— OG7
C4B63_14g250 ⚠
Anaphase-promoting complex subunit 3
— OG7
C4B63_28g109 ⚠
conserved hypothetical protein
— OG7
C4B63_49g186 ⚠
ccr4-not transcription complex subunit
— OG7
C4B63_46g32 ⚠
E3 ubiquitin-protein ligase HERC2
— OG7
C4B63_7g67 ⚠
Sec7 guanine-nucleotide exchange factor
— OG7
C4B63_17g277 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_127g30 ⚠
Flagellum attachment zone protein 14
— OG7
C4B63_13g243 ⚠
intraflagellar transport protein 122B(fragmen
— OG7
C4B63_10g132 ⚠
conserved hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.