C4B63_43g187

structural maintenance of chromosome protein 4
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101113 OG7: OG7_0001761 277 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 277 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_2g62 ⚠
conserved hypothetical protein
— OG7
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
C4B63_2g61 ⚠
conserved hypothetical protein
— OG7
C4B63_32g248 ⚠
conserved hypothetical protein
— OG7
C4B63_199g20 ⚠
conserved hypothetical protein
— OG7
C4B63_42g107 ⚠
conserved hypothetical protein
— OG7
C4B63_51g192 ⚠
protein kinase A regulatory subunit
— OG7
C4B63_127g31 ⚠
Flagellum attachment zone protein 14
— OG7
C4B63_4g478 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
C4B63_358g16 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_40g106 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
C4B63_63g32 ⚠
adaptin-related protein-like
— OG7
C4B63_9g328 ⚠
conserved hypothetical protein
— OG7
C4B63_14g147 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
C4B63_14g87 ⚠
conserved hypothetical protein
— OG7
C4B63_19g266 ⚠
conserved hypothetical protein
— OG7
C4B63_30g181 ⚠
rRNA methyltransferase 1, mitochondrial
— OG7
C4B63_104g75 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_104g76 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_14g103 ⚠
beta adaptin
— OG7
C4B63_17g49 ⚠
Pab1p-dependent poly(A) ribonuclease subunit
— OG7
C4B63_168g31 ⚠
dynein arm light chain
— OG7
C4B63_81g52 ⚠
Gamma-tubulin complex component 3-like protei
— OG7
C4B63_48g37 ⚠
conserved hypothetical protein
— OG7
C4B63_7g234 ⚠
Signal recognition particle subunit SRP68
— OG7
C4B63_42g198 ⚠
conserved hypothetical protein
— OG7
C4B63_31g100 ⚠
conserved hypothetical protein
— OG7
C4B63_263g1 ⚠
conserved hypothetical protein
— OG7
C4B63_7g312 ⚠
conserved hypothetical protein
— OG7
C4B63_2g63 ⚠
conserved hypothetical protein
— OG7
C4B63_43g154 ⚠
TRAF3-interacting protein 1
— OG7
C4B63_2g83 ⚠
ubiquitin hydrolase
— OG7
C4B63_9g446 ⚠
Probable methyltransferase TARBP1
— OG7
C4B63_9g327 ⚠
conserved hypothetical protein
— OG7
C4B63_94g56 ⚠
conserved hypothetical protein
— OG7
C4B63_206g11 ⚠
ABC transporter
— OG7
C4B63_31g166 ⚠
histone deacetylase 4
— OG7
C4B63_4g202 ⚠
Periodic tryptophan protein 2 homolog
— OG7
C4B63_127g51 ⚠
acetyl-CoA carboxylase
— OG7
C4B63_42g199 ⚠
conserved hypothetical protein
— OG7
C4B63_52g168 ⚠
Cilia- and flagella-associated protein 44
— OG7
C4B63_25g220 ⚠
5'-3' exoribonuclease B
— OG7
C4B63_4g502 ⚠
ABC transporter
— OG7
C4B63_113g34 ⚠
ABC transporter
— OG7
C4B63_323g7 ⚠
Cilia- and flagella-associated protein 58
— OG7
C4B63_22g288 ⚠
Midasin
— OG7
C4B63_7g62 ⚠
Cilia- and flagella-associated protein 58
— OG7
C4B63_40g188 ⚠
Cilia- and flagella-associated protein 58
— OG7
C4B63_156g7 ⚠
Cilia- and flagella-associated protein 58
— OG7
C4B63_23g265 ⚠
conserved hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.