C4B63_63g32

adaptin-related protein-like
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100684 OG7: OG7_0001921 235 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 235 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_7g395 ⚠
conserved hypothetical protein
— Both
C4B63_18g183 ⚠
damage-specific DNA binding protein
— OG7
C4B63_4g202 ⚠
Periodic tryptophan protein 2 homolog
— OG7
C4B63_43g196 ⚠
adenylate kinase 1
— OG7
C4B63_4g200 ⚠
conserved hypothetical protein
— OG7
C4B63_4g201 ⚠
Protein ILITYHIA
— OG7
C4B63_44g236 ⚠
conserved hypothetical protein
— OG7
C4B63_7g234 ⚠
Signal recognition particle subunit SRP68
— OG7
C4B63_127g51 ⚠
acetyl-CoA carboxylase
— OG7
C4B63_32g232 ⚠
conserved hypothetical protein
— OG7
C4B63_40g156 ⚠
Alkylated DNA repair dioxygenase AlkB
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_9g291 ⚠
conserved hypothetical protein
— OG7
C4B63_267g12 ⚠
conserved hypothetical protein
— OG7
C4B63_12g314 ⚠
conserved hypothetical protein
— OG7
C4B63_81g97 ⚠
conserved hypothetical protein
— OG7
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_17g277 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_17g278 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_7g424 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— OG7
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_22g113 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_63g101 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
C4B63_354g8 ⚠
damage-specific DNA binding protein
— OG7
C4B63_186g23 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG7
C4B63_9g329 ⚠
Beige/BEACH domain
— OG7
C4B63_358g16 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_255g16 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_48g124 ⚠
neurobeachin/beige protein
— OG7
C4B63_48g123 ⚠
neurobeachin/beige protein
— OG7
C4B63_55g67 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
C4B63_9g327 ⚠
conserved hypothetical protein
— OG7
C4B63_321g29 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_48g122 ⚠
neurobeachin/beige protein
— OG7
C4B63_47g56 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_112g13 ⚠
neurobeachin/beige-like protein(fragment)
— OG7
C4B63_16g132 ⚠
DNA polymerase theta (helicase domain only)
— OG7
C4B63_51g90 ⚠
ATP-dependent RNA helicase
— OG7
C4B63_25g185 ⚠
ATP-dependent RNA helicase
— OG7
C4B63_49g186 ⚠
ccr4-not transcription complex subunit
— OG7
C4B63_70g86 ⚠
conserved hypothetical protein
— OG7
C4B63_21g86 ⚠
conserved hypothetical protein
— OG7
C4B63_12g8 ⚠
conserved hypothetical protein
— OG7
C4B63_354g7 ⚠
damage-specific DNA binding protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.