C4B63_186g23

ATP-dependent DEAD/H RNA helicase(fragment)
Trypanosoma cruzi Dm28c 2018 OG6: OG6_104328 OG7: OG7_0001850 172 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 172 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_2g155 ⚠
PRP8 protein homologue
— OG7
C4B63_2g154 ⚠
PRP8 protein homologue
— OG7
C4B63_127g51 ⚠
acetyl-CoA carboxylase
— OG7
C4B63_31g57 ⚠
zinc-finger motif, C2HC5-type/ASCH domain con
— OG7
C4B63_48g169 ⚠
adenylate kinase 1
— OG7
C4B63_354g7 ⚠
damage-specific DNA binding protein
— OG7
C4B63_112g14 ⚠
neurobeachin/beige-like protein
— OG7
C4B63_113g35 ⚠
mitogen activated protein kinase
— OG7
C4B63_17g278 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_12g219 ⚠
adaptin-related protein-like
— OG7
C4B63_31g46 ⚠
structural maintenance of chromosome 3 protei
— OG7
C4B63_321g29 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_10g507 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
C4B63_44g149 ⚠
conserved hypothetical protein
— OG7
C4B63_20g19 ⚠
Nucleoporin
— OG7
C4B63_16g22 ⚠
conserved hypothetical protein
— OG7
C4B63_16g20 ⚠
conserved hypothetical protein
— OG7
C4B63_4g200 ⚠
conserved hypothetical protein
— OG7
C4B63_2g729 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
C4B63_47g56 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_2g91 ⚠
General vesicular transport factor p115
— OG7
C4B63_18g183 ⚠
damage-specific DNA binding protein
— OG7
C4B63_8g44 ⚠
conserved hypothetical protein
— OG7
C4B63_48g122 ⚠
neurobeachin/beige protein
— OG7
C4B63_194g21 ⚠
DNA-directed RNA polymerase III
— OG7
C4B63_32g333 ⚠
conserved hypothetical protein
— OG7
C4B63_19g267 ⚠
Right handed beta helix region containing pro
— OG7
C4B63_38g67 ⚠
adenylate kinase
— OG7
C4B63_63g93 ⚠
Cell division control protein 48
— OG7
C4B63_7g395 ⚠
conserved hypothetical protein
— OG7
C4B63_17g277 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_112g13 ⚠
neurobeachin/beige-like protein(fragment)
— OG7
C4B63_279g5 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_192g23 ⚠
conserved hypothetical protein
— OG7
C4B63_16g21 ⚠
conserved hypothetical protein
— OG7
C4B63_26g318 ⚠
conserved hypothetical protein
— OG7
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_19g82 ⚠
RNA polymerase I second largest subunit
— OG7
C4B63_354g8 ⚠
damage-specific DNA binding protein
— OG7
C4B63_136g39 ⚠
conserved hypothetical protein
— OG7
C4B63_17g180 ⚠
RNA-binding protein,
— OG7
C4B63_2g527 ⚠
proteasome regulatory non-ATPase subunit 3
— OG7
C4B63_70g99 ⚠
conserved hypothetical protein
— OG7
C4B63_21g86 ⚠
conserved hypothetical protein
— OG7
C4B63_199g20 ⚠
conserved hypothetical protein
— OG7
C4B63_21g113 ⚠
conserved hypothetical protein
— OG7
C4B63_80g25 ⚠
ubiquitin hydrolase
— OG7
C4B63_13g155 ⚠
elongation factor 2
— OG7
C4B63_13g154 ⚠
elongation factor 2
— OG7
C4B63_9g523 ⚠
U5 small nuclear ribonucleoprotein component
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.