C4B63_44g149

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_111983 OG7: OG7_0009773 196 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 196 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_40g114
glycosyl hydrolase
— Both
C4B63_4g201 ⚠
Protein ILITYHIA
— +2 more Both
C4B63_16g154
exosome component CSL4
— Both
C4B63_7g87
Alpha,alpha-trehalose phosphorylase
— Both
C4B63_4g200 ⚠
conserved hypothetical protein
— +2 more Both
C4B63_57g120
Flagellar Member 1
— Both
C4B63_17g278 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_25g186 ⚠
formin
— OG7
C4B63_340g8 ⚠
conserved hypothetical protein
— OG7
C4B63_22g113 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_23g143 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_63g32 ⚠
adaptin-related protein-like
— OG7
C4B63_63g101 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
C4B63_30g181 ⚠
rRNA methyltransferase 1, mitochondrial
— OG7
C4B63_14g103 ⚠
beta adaptin
— OG7
C4B63_304g10 ⚠
DNA-directed RNA polymerase III subunit C11
— OG7
C4B63_249g22 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_7g424 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— OG7
C4B63_4g2794c ⚠
DNA-directed RNA polymerase III subunit C11
— OG7
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_282g10 ⚠
conserved hypothetical protein
— Both
C4B63_282g11 ⚠
conserved hypothetical protein
— Both
C4B63_6g393 ⚠
conserved hypothetical protein
— Both
C4B63_6g490
Vacuole membrane protein 1
— Both
C4B63_31g109 ⚠
ribose-phosphate pyrophosphokinase
— Both
C4B63_192g23 ⚠
conserved hypothetical protein
— Both
C4B63_40g87
WD40 repeat-containing protein
— Both
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— Both
C4B63_40g106 ⚠
Adaptor protein complex AP-3 subunit beta-3
— Both
C4B63_7g127
conserved hypothetical protein
— Both
C4B63_20g157
NADH dehydrogenase subunit NI8M
— Both
C4B63_326g16 ⚠
dihydrolipoamide dehydrogenase
— Both
C4B63_358g1 ⚠
dihydrolipoamide dehydrogenase
— Both
C4B63_44g129
protein phosphatase
— OG6
C4B63_127g51
acetyl-CoA carboxylase
— Both
C4B63_249g23 ⚠
dihydrolipoamide dehydrogenase
— Both
C4B63_4g128
Vacuolar protein 8
— Both
C4B63_40g80 ⚠
DNA-directed RNA polymerase I subunit
— Both
C4B63_9g291
conserved hypothetical protein
— Both
C4B63_17g49
Pab1p-dependent poly(A) ribonuclease subunit
— Both
C4B63_7g395
conserved hypothetical protein
— Both
C4B63_10g280 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_2g91
General vesicular transport factor p115
— Both
C4B63_40g156
Alkylated DNA repair dioxygenase AlkB
— Both
C4B63_20g19
Nucleoporin
— Both
C4B63_54g15
Fatty acid oxidation complex subunit alpha
— Both
C4B63_7g1173c
ubiquitin
— OG6
C4B63_9g446 ⚠
Probable methyltransferase TARBP1
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.