C4B63_340g8

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_144386 OG7: OG7_0002388 195 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 195 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_51g196 ⚠
conserved hypothetical protein
— Both
C4B63_51g197 ⚠
conserved hypothetical protein
— Both
C4B63_43g196 ⚠
adenylate kinase 1
— OG7
C4B63_8g44 ⚠
conserved hypothetical protein
— OG7
C4B63_2g431 ⚠
GTPase protein
— OG7
C4B63_128g61 ⚠
50S ribosome-binding GTPase
— OG7
C4B63_128g62 ⚠
50S ribosome-binding GTPase
— OG7
C4B63_91g35 ⚠
GTPase
— OG7
C4B63_8g202 ⚠
GTP-binding protein
— OG7
C4B63_56g32 ⚠
GTPase
— OG7
C4B63_128g63 ⚠
GTP-binding protein
— OG7
C4B63_11g100 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG7
C4B63_107g4 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG7
C4B63_17g49 ⚠
Pab1p-dependent poly(A) ribonuclease subunit
— OG7
C4B63_4g170 ⚠
Cilia- and flagella-associated protein 74
— OG7
C4B63_16g21 ⚠
conserved hypothetical protein
— OG7
C4B63_16g20 ⚠
conserved hypothetical protein
— OG7
C4B63_16g22 ⚠
conserved hypothetical protein
— OG7
C4B63_38g67 ⚠
adenylate kinase
— OG7
C4B63_60g174 ⚠
adenylate kinase
— OG7
C4B63_48g169 ⚠
adenylate kinase 1
— OG7
C4B63_15g5 ⚠
zinc-finger CCCH domain containing protein 11
— OG7
C4B63_12g2035c ⚠
zinc-finger protein 2
— OG7
C4B63_192g4 ⚠
adenylate kinase 1
— OG7
C4B63_72g94 ⚠
ribosomal RNA processing protein 40
— OG7
C4B63_42g232 ⚠
ubiquitin hydrolase
— OG7
C4B63_397g11 ⚠
zinc-finger CCCH domain containing protein 11
— OG7
C4B63_247g23 ⚠
damage-specific DNA binding protein
— OG7
C4B63_17g284 ⚠
ATP-dependent DNA DEAD/DEAH box helicase
— OG7
C4B63_259g8 ⚠
DNA polymerase theta (helicase domain only)
— OG7
C4B63_63g93 ⚠
Cell division control protein 48
— OG7
C4B63_31g220 ⚠
conserved hypothetical protein
— OG7
C4B63_70g99 ⚠
conserved hypothetical protein
— OG7
C4B63_70g86 ⚠
conserved hypothetical protein
— OG7
C4B63_21g86 ⚠
conserved hypothetical protein
— OG7
C4B63_12g8 ⚠
conserved hypothetical protein
— OG7
C4B63_49g186 ⚠
ccr4-not transcription complex subunit
— OG7
C4B63_56g93 ⚠
Splicing factor 3B subunit 3
— OG7
C4B63_354g7 ⚠
damage-specific DNA binding protein
— OG7
C4B63_127g51 ⚠
acetyl-CoA carboxylase
— OG7
C4B63_326g16 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_83g24 ⚠
zinc-finger (CCCH type) protein
— OG7
C4B63_4g200 ⚠
conserved hypothetical protein
— OG7
C4B63_4g201 ⚠
Protein ILITYHIA
— OG7
C4B63_44g236 ⚠
conserved hypothetical protein
— OG7
C4B63_12g314 ⚠
conserved hypothetical protein
— OG7
C4B63_18g183 ⚠
damage-specific DNA binding protein
— OG7
C4B63_354g8 ⚠
damage-specific DNA binding protein
— OG7
C4B63_4g202 ⚠
Periodic tryptophan protein 2 homolog
— OG7
C4B63_267g12 ⚠
conserved hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.