C4B63_70g86

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_147362 OG7: OG7_0037845 170 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 170 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_20g157
NADH dehydrogenase subunit NI8M
— Both
C4B63_48g124 ⚠
neurobeachin/beige protein
— OG7
C4B63_57g120
Flagellar Member 1
— Both
C4B63_6g108
DNA replication licensing factor MCM2
— OG6
C4B63_282g10 ⚠
conserved hypothetical protein
— Both
C4B63_19g267 ⚠
Right handed beta helix region containing pro
— Both
C4B63_32g232
conserved hypothetical protein
— Both
C4B63_31g220
conserved hypothetical protein
— Both
C4B63_70g112 ⚠
pumilio-repeat, RNA-binding protein(fragment)
— Both
C4B63_7g395
conserved hypothetical protein
— Both
C4B63_81g97
conserved hypothetical protein
— Both
C4B63_40g87
WD40 repeat-containing protein
— Both
C4B63_267g12 ⚠
conserved hypothetical protein
— Both
C4B63_19g82 ⚠
RNA polymerase I second largest subunit
— Both
C4B63_49g173 ⚠
conserved hypothetical protein
— Both
C4B63_17g90 ⚠
T-complex protein 1, beta subunit
— OG6
C4B63_16g108 ⚠
chaperonin/T-complex protein 1 gamma subunit
— OG6
C4B63_2g66
helicase
— OG6
C4B63_38g69
chaperone DNAJ protein
— Both
C4B63_24g264 ⚠
conserved hypothetical protein
— Both
C4B63_56g43 ⚠
conserved hypothetical protein
— Both
C4B63_91g44 ⚠
conserved hypothetical protein
— Both
C4B63_42g256
conserved hypothetical protein
— Both
C4B63_230g27 ⚠
NADH dehydrogenase subunit NB6M
— Both
C4B63_6g387 ⚠
NADH dehydrogenase subunit NB6M
— Both
C4B63_56g38 ⚠
nuclear receptor binding factor
— Both
C4B63_276g9 ⚠
Alcohol Dehydrogenasa
— Both
C4B63_9g262
conserved hypothetical protein
— Both
C4B63_147g69 ⚠
conserved hypothetical protein
— Both
C4B63_42g184
fatty-acyl-CoA synthase
— Both
C4B63_33g147 ⚠
NADH-ubiquinone oxidoreductase, mitochondrial
— Both
C4B63_29g185 ⚠
NADH-ubiquinone oxidoreductase, mitochondrial
— Both
C4B63_91g39 ⚠
nuclear receptor binding factor
— Both
C4B63_12g385
Acyl carrier protein, mitochondrial
— Both
C4B63_10g448
NADH-ubiquinone oxidoreductase complex I subu
— Both
C4B63_61g128
NADH-ubiquinone oxidoreductase, mitochondrial
— Both
C4B63_75g55
conserved hypothetical protein
— Both
C4B63_21g79
conserved hypothetical protein
— Both
C4B63_72g103 ⚠
nuclear receptor binding factor
— Both
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— OG7
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_9g329 ⚠
Beige/BEACH domain
— OG7
C4B63_7g424 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_32g333 ⚠
conserved hypothetical protein
— OG7
C4B63_48g122 ⚠
neurobeachin/beige protein
— OG7
C4B63_194g21 ⚠
DNA-directed RNA polymerase III
— OG7
C4B63_10g280 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_87g26 ⚠
formin homology 2 (FH2) domain protein
— OG7
C4B63_279g5 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.