C4B63_70g112

pumilio-repeat, RNA-binding protein(fragment)
Trypanosoma cruzi Dm28c 2018 OG6: OG6_157090 OG7: OG7_0051081 107 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 107 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_30g181 ⚠
rRNA methyltransferase 1, mitochondrial
— OG7
C4B63_32g232 ⚠
conserved hypothetical protein
— Both
C4B63_31g220 ⚠
conserved hypothetical protein
— Both
C4B63_7g395 ⚠
conserved hypothetical protein
— Both
C4B63_40g87 ⚠
WD40 repeat-containing protein
— Both
C4B63_81g97 ⚠
conserved hypothetical protein
— Both
C4B63_267g12 ⚠
conserved hypothetical protein
— Both
C4B63_19g82 ⚠
RNA polymerase I second largest subunit
— Both
C4B63_49g173 ⚠
conserved hypothetical protein
— Both
C4B63_45g218 ⚠
conserved hypothetical protein
— Both
C4B63_45g216 ⚠
conserved hypothetical protein
— Both
C4B63_45g217 ⚠
WD40 repeat protein
— Both
C4B63_70g86 ⚠
conserved hypothetical protein
— Both
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— OG7
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_9g329 ⚠
Beige/BEACH domain
— OG7
C4B63_7g424 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_48g124 ⚠
neurobeachin/beige protein
— OG7
C4B63_48g123 ⚠
neurobeachin/beige protein
— OG7
C4B63_44g250 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_279g6 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_9g327 ⚠
conserved hypothetical protein
— OG7
C4B63_249g22 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_14g103 ⚠
beta adaptin
— OG7
C4B63_104g76 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_104g75 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_321g29 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_8g58 ⚠
Dynein assembly factor 1, axonemal homolog
— OG7
C4B63_17g277 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_279g5 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_112g13 ⚠
neurobeachin/beige-like protein(fragment)
— OG7
C4B63_87g26 ⚠
formin homology 2 (FH2) domain protein
— OG7
C4B63_32g333 ⚠
conserved hypothetical protein
— OG7
C4B63_194g21 ⚠
DNA-directed RNA polymerase III
— OG7
C4B63_10g280 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_48g122 ⚠
neurobeachin/beige protein
— OG7
C4B63_12g8 ⚠
conserved hypothetical protein
— OG7
C4B63_47g56 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_17g278 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_255g16 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_25g186 ⚠
formin
— OG7
C4B63_9g328 ⚠
conserved hypothetical protein
— OG7
C4B63_63g32 ⚠
adaptin-related protein-like
— OG7
C4B63_358g16 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_63g101 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
C4B63_23g143 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_112g14 ⚠
neurobeachin/beige-like protein
— OG7
C4B63_326g15 ⚠
dihydrolipoamide dehydrogenase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.