C4B63_8g58

Dynein assembly factor 1, axonemal homolog
Trypanosoma cruzi Dm28c 2018 OG6: OG6_146995 OG7: OG7_0007518 133 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 133 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_144g29 ⚠
conserved hypothetical protein
— OG7
C4B63_6g102 ⚠
conserved hypothetical protein
— OG7
C4B63_4g207 ⚠
conserved hypothetical protein
— OG7
C4B63_4g205 ⚠
conserved hypothetical protein
— OG7
C4B63_6g252 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_25g218 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_25g219 ⚠
conserved hypothetical protein
— OG7
C4B63_42g253 ⚠
conserved hypothetical protein
— OG7
C4B63_25g290 ⚠
60S ribosomal protein
— OG7
C4B63_92g59 ⚠
60S ribosomal protein(fragment)
— OG7
C4B63_208g30 ⚠
60S ribosomal protein(fragment)
— OG7
C4B63_127g65 ⚠
60S ribosomal protein(fragment)
— OG7
C4B63_63g81 ⚠
protein transport protein Sec23A
— OG7
C4B63_78g10 ⚠
conserved hypothetical protein
— OG7
C4B63_78g13 ⚠
Proteasome activator complex subunit 4
— OG7
C4B63_78g9 ⚠
conserved hypothetical protein
— OG7
C4B63_234g11 ⚠
conserved hypothetical protein
— OG7
C4B63_78g12 ⚠
conserved hypothetical protein
— OG7
C4B63_78g11 ⚠
conserved hypothetical protein
— OG7
C4B63_157g19 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_148g32 ⚠
conserved hypothetical protein
— OG7
C4B63_171g22 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_271g10 ⚠
conserved hypothetical protein
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_9g442 ⚠
kinteoplast poly(A) polymerase complex 1 subu
— OG7
C4B63_2g407 ⚠
Cilia- and flagella-associated protein 91
— OG7
C4B63_21g245 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_4g577 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_40g78 ⚠
conserved hypothetical protein
— OG7
C4B63_2g782 ⚠
ATP-dependent RNA helicase
— OG7
C4B63_94g58 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_43g202 ⚠
hook complex protein, conserved
— OG7
C4B63_224g16 ⚠
conserved hypothetical protein
— OG7
C4B63_30g245 ⚠
conserved hypothetical protein
— OG7
C4B63_10g514 ⚠
WD domain, G-beta repeat
— OG7
C4B63_52g136 ⚠
Cytoplasmic dynein 1 intermediate chain
— OG7
C4B63_41g119 ⚠
conserved hypothetical protein
— OG7
C4B63_9g306 ⚠
dynein intermediate chain
— OG7
C4B63_28g54 ⚠
Dynein intermediate chain 1, axonemal
— OG7
C4B63_41g125 ⚠
conserved hypothetical protein
— OG7
C4B63_41g122 ⚠
conserved hypothetical protein
— OG7
C4B63_70g112 ⚠
pumilio-repeat, RNA-binding protein(fragment)
— OG7
C4B63_19g112 ⚠
conserved hypothetical protein
— OG7
C4B63_26g307 ⚠
conserved hypothetical protein
— OG7
C4B63_26g308 ⚠
conserved hypothetical protein
— OG7
C4B63_133g52 ⚠
conserved hypothetical protein
— OG7
C4B63_41g128 ⚠
conserved hypothetical protein
— OG7
C4B63_10g524 ⚠
nuclear transcription factor
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.