C4B63_30g245

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_139469 OG7: OG7_0001911 107 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 107 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_197g36 ⚠
conserved hypothetical protein
— OG7
C4B63_43g202 ⚠
hook complex protein, conserved
— OG7
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_2g816 ⚠
conserved hypothetical protein
— OG7
C4B63_9g322
translation initiation factor IF-2
— OG7
C4B63_61g82 ⚠
Chromosome transmission fidelity protein 18 h
— OG7
C4B63_51g105
conserved hypothetical protein
— OG7
C4B63_224g16 ⚠
conserved hypothetical protein
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_142g11 ⚠
Protein shuttle craft
— OG7
C4B63_42g204 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_2g551 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
C4B63_28g129 ⚠
replication factor C, subunit 1
— OG7
C4B63_18g277 ⚠
replication factor C, subunit 2
— OG7
C4B63_32g239 ⚠
tubulin folding cofactor D
— OG7
C4B63_31g99
WD repeat-containing protein 17
— OG7
C4B63_1g73 ⚠
conserved hypothetical protein
— OG7
C4B63_12g213 ⚠
zinc-finger ccch and cchc domain-containing p
— OG7
C4B63_271g80c ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
C4B63_23g186
aspartyl aminopeptidase
— OG7
C4B63_7g382 ⚠
ubiquitin-protein ligase
— OG7
C4B63_2g88 ⚠
ubiquitin-protein ligase
— OG7
C4B63_7g79 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_8g219 ⚠
protein farnesyltransferase
— OG7
C4B63_41g73 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_25g218 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_8g190 ⚠
conserved hypothetical protein
— OG7
C4B63_23g275 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_10g524 ⚠
nuclear transcription factor
— OG7
C4B63_2g1123c ⚠
small nuclear ribonucleoprotein Sm-F
— OG7
C4B63_6g517 ⚠
geranylgeranyl transferase type II beta subun
— OG7
C4B63_8g58 ⚠
Dynein assembly factor 1, axonemal homolog
— OG7
C4B63_12g208
leucine-rich repeat protein (LRRP)
— OG7
C4B63_25g219 ⚠
conserved hypothetical protein
— OG7
C4B63_11g283c ⚠
U6 snRNA-associated Sm-like protein LSm8
— OG7
C4B63_32g238 ⚠
tubulin folding cofactor D
— OG7
C4B63_39g340 ⚠
replication factor C, subunit 4
— OG7
C4B63_330g12 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_4g269
conserved hypothetical protein
— OG7
C4B63_82g92 ⚠
conserved hypothetical protein
— OG7
C4B63_248g25 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_8g54
conserved hypothetical protein
— OG7
C4B63_41g128 ⚠
conserved hypothetical protein
— OG7
C4B63_43g1065c ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
C4B63_6g269 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_513g4 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_54g82
conserved hypothetical protein
— OG7
C4B63_84g82
DNA mismatch repair protein MSH2
— OG7
C4B63_282g21 ⚠
conserved hypothetical protein
— OG7
C4B63_102g53
conserved hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.