C4B63_148g32

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_136912 OG7: OG7_0043086 99 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 99 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_35g186 ⚠
50S ribosomal protein L17
— Both
C4B63_4g577 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_46g55 ⚠
conserved hypothetical protein
— OG7
C4B63_49g115 ⚠
conserved hypothetical protein
— Both
C4B63_42g253 ⚠
conserved hypothetical protein
— Both
C4B63_140g33 ⚠
conserved hypothetical protein
— Both
C4B63_2g805 ⚠
SpoU rRNA Methylase family
— Both
C4B63_18g273 ⚠
conserved hypothetical protein
— Both
C4B63_25g114 ⚠
conserved hypothetical protein
— Both
C4B63_129g45 ⚠
conserved hypothetical protein
— Both
C4B63_16g127 ⚠
conserved hypothetical protein
— Both
C4B63_32g212 ⚠
Pentatricopeptide repeat-containing protein A
— Both
C4B63_49g57 ⚠
cyclophilin
— OG6
C4B63_2g551 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
C4B63_8g543 ⚠
small GTP-binding protein
— Both
C4B63_293g5 ⚠
cyclophilin
— OG6
C4B63_16g126 ⚠
conserved hypothetical protein
— Both
C4B63_31g78 ⚠
conserved hypothetical protein
— Both
C4B63_19g35 ⚠
conserved hypothetical protein
— Both
C4B63_93g62 ⚠
Pentatricopeptide repeat-containing protein
— Both
C4B63_44g107 ⚠
conserved hypothetical protein
— Both
C4B63_32g215 ⚠
Pentatricopeptide repeat-containing protein A
— Both
C4B63_16g110 ⚠
conserved hypothetical protein
— Both
C4B63_6g1087c ⚠
ribosomal protein S29
— Both
C4B63_330g3c ⚠
ribosomal protein S29
— Both
C4B63_300g15 ⚠
Vps51/Vps67
— OG7
C4B63_112g13 ⚠
neurobeachin/beige-like protein(fragment)
— OG7
C4B63_112g14 ⚠
neurobeachin/beige-like protein
— OG7
C4B63_9g328 ⚠
conserved hypothetical protein
— OG7
C4B63_9g327 ⚠
conserved hypothetical protein
— OG7
C4B63_9g329 ⚠
Beige/BEACH domain
— OG7
C4B63_51g200 ⚠
mitochondrial DNA polymerase I protein B
— OG7
C4B63_28g54 ⚠
Dynein intermediate chain 1, axonemal
— OG7
C4B63_9g306 ⚠
dynein intermediate chain
— OG7
C4B63_52g136 ⚠
Cytoplasmic dynein 1 intermediate chain
— OG7
C4B63_10g514 ⚠
WD domain, G-beta repeat
— OG7
C4B63_8g58 ⚠
Dynein assembly factor 1, axonemal homolog
— OG7
C4B63_300g16 ⚠
conserved hypothetical protein
— OG7
C4B63_6g1078c ⚠
ribosomal protein S29
— Both
C4B63_34g318 ⚠
Vps51/Vps67
— OG7
C4B63_127g65 ⚠
60S ribosomal protein(fragment)
— OG7
C4B63_208g30 ⚠
60S ribosomal protein(fragment)
— OG7
C4B63_92g59 ⚠
60S ribosomal protein(fragment)
— OG7
C4B63_4g205 ⚠
conserved hypothetical protein
— OG7
C4B63_4g207 ⚠
conserved hypothetical protein
— OG7
C4B63_330g12 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_513g4 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_6g269 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_171g22 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_157g19 ⚠
eukaryotic translation initiation factor 4E (
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.