C4B63_28g54

Dynein intermediate chain 1, axonemal
Trypanosoma cruzi Dm28c 2018 OG6: OG6_104441 OG7: OG7_0002233 65 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 65 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_20g322 ⚠
conserved hypothetical protein
— OG7
C4B63_18g58 ⚠
Hydin,flagellar component
— OG7
C4B63_63g7 ⚠
eukaryotic translation initiation factor 3 su
— OG7
C4B63_93g76 ⚠
40S ribosomal protein S11
— OG7
C4B63_26g308 ⚠
conserved hypothetical protein
— OG7
C4B63_2g405 ⚠
conserved hypothetical protein
— OG7
C4B63_4g207 ⚠
conserved hypothetical protein
— OG7
C4B63_6g102 ⚠
conserved hypothetical protein
— OG7
C4B63_40g163 ⚠
leucine-rich repeat protein (LRRP)
— OG7
C4B63_17g241 ⚠
conserved hypothetical protein
— OG7
C4B63_40g78 ⚠
conserved hypothetical protein
— OG7
C4B63_7g56 ⚠
Protein transport protein sec71
— OG7
C4B63_81g15 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_43g163 ⚠
40S ribosomal protein S11
— OG7
C4B63_2g407 ⚠
Cilia- and flagella-associated protein 91
— OG7
C4B63_87g20 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_26g307 ⚠
conserved hypothetical protein
— OG7
C4B63_133g52 ⚠
conserved hypothetical protein
— OG7
C4B63_7g421 ⚠
coatomer alpha subunit
— OG7
C4B63_7g67 ⚠
Sec7 guanine-nucleotide exchange factor
— OG7
C4B63_42g253 ⚠
conserved hypothetical protein
— OG7
C4B63_8g58 ⚠
Dynein assembly factor 1, axonemal homolog
— OG7
C4B63_7g68 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_286g18 ⚠
eukaryotic translation initiation factor 3 su
— OG7
C4B63_19g112 ⚠
conserved hypothetical protein
— OG7
C4B63_2g215 ⚠
PIH1 domain-containing protein 1
— OG7
C4B63_4g265 ⚠
pre-RNA processing PIH1/Nop17
— OG7
C4B63_4g264 ⚠
Protein kintoun
— OG7
C4B63_4g526 ⚠
conserved hypothetical protein
— OG7
C4B63_24g272 ⚠
Zn-finger in Ran binding protein and others/S
— OG7
C4B63_52g168 ⚠
Cilia- and flagella-associated protein 44
— OG7
C4B63_24g273 ⚠
Probable E3 ubiquitin-protein ligase HERC1
— OG7
C4B63_2g454 ⚠
Tubulin cofactor C domain-containing protein
— OG7
C4B63_234g11 ⚠
conserved hypothetical protein
— OG7
C4B63_43g211 ⚠
conserved hypothetical protein
— OG7
C4B63_46g55 ⚠
conserved hypothetical protein
— OG7
C4B63_11g83 ⚠
Eukaryotic translation initiation factor 3 su
— OG7
C4B63_69g60 ⚠
conserved hypothetical protein
— OG7
C4B63_144g29 ⚠
conserved hypothetical protein
— OG7
C4B63_137g10 ⚠
Coatomer subunit gamma
— OG7
C4B63_6g279 ⚠
Coatomer subunit gamma
— OG7
C4B63_22g173 ⚠
coatomer beta subunit
— OG7
C4B63_25g290 ⚠
60S ribosomal protein
— OG7
C4B63_92g59 ⚠
60S ribosomal protein(fragment)
— OG7
C4B63_208g30 ⚠
60S ribosomal protein(fragment)
— OG7
C4B63_127g65 ⚠
60S ribosomal protein(fragment)
— OG7
C4B63_78g10 ⚠
conserved hypothetical protein
— OG7
C4B63_78g13 ⚠
Proteasome activator complex subunit 4
— OG7
C4B63_78g9 ⚠
conserved hypothetical protein
— OG7
C4B63_43g210 ⚠
conserved hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.