C4B63_7g395

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_147115 OG7: OG7_0043222 275 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 275 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_12g219 ⚠
adaptin-related protein-like
— OG7
C4B63_63g32 ⚠
adaptin-related protein-like
— Both
C4B63_14g103 ⚠
beta adaptin
— OG7
C4B63_40g106 ⚠
Adaptor protein complex AP-3 subunit beta-3
— Both
C4B63_2g83 ⚠
ubiquitin hydrolase
— OG7
C4B63_2g502 ⚠
ubiquitin carboxyl-terminal hydrolase
— OG7
C4B63_252g9 ⚠
ubiquitin carboxyl-terminal hydrolase
— OG7
C4B63_80g25 ⚠
ubiquitin hydrolase
— Both
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— Both
C4B63_48g124 ⚠
neurobeachin/beige protein
— OG7
C4B63_255g16 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_358g16 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_9g329 ⚠
Beige/BEACH domain
— OG7
C4B63_104g75 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_104g76 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_112g14 ⚠
neurobeachin/beige-like protein
— OG7
C4B63_2g75 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_2g74 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_9g328 ⚠
conserved hypothetical protein
— OG7
C4B63_9g487 ⚠
histone deacetylase
— OG7
C4B63_13g160 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
C4B63_23g264 ⚠
6-phosphofructo-2-kinase 1
— OG7
C4B63_45g121 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
C4B63_2g380 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
C4B63_59g118 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
C4B63_14g147 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
C4B63_279g5 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_194g21 ⚠
DNA-directed RNA polymerase III
— OG7
C4B63_279g6 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_44g250 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_87g26 ⚠
formin homology 2 (FH2) domain protein
— OG7
C4B63_25g186 ⚠
formin
— OG7
C4B63_8g496
conserved hypothetical protein
— OG7
C4B63_2g450 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_32g238 ⚠
tubulin folding cofactor D
— Both
C4B63_32g239 ⚠
tubulin folding cofactor D
— Both
C4B63_42g187
conserved hypothetical protein
— Both
C4B63_282g10 ⚠
conserved hypothetical protein
— Both
C4B63_282g11 ⚠
conserved hypothetical protein
— Both
C4B63_19g265 ⚠
F-box protein dre-1
— Both
C4B63_35g167 ⚠
tubulin tyrosine ligase
— OG6
C4B63_60g127 ⚠
tubulin tyrosine ligase
— OG6
C4B63_160g6 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_60g126 ⚠
tubulin tyrosine ligase
— OG6
C4B63_31g274 ⚠
tubulin tyrosine ligase
— OG6
C4B63_32g232
conserved hypothetical protein
— Both
C4B63_52g72
WD repeat-containing protein 3
— Both
C4B63_19g267 ⚠
Right handed beta helix region containing pro
— Both
C4B63_21g277
conserved hypothetical protein
— Both
C4B63_7g312 ⚠
conserved hypothetical protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.