C4B63_35g167

tubulin tyrosine ligase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_104876 OG7: OG7_0001164 59 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 59 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_40g156 ⚠
Alkylated DNA repair dioxygenase AlkB
— OG6
C4B63_4g202 ⚠
Periodic tryptophan protein 2 homolog
— OG6
C4B63_249g23 ⚠
dihydrolipoamide dehydrogenase
— OG6
C4B63_4g128 ⚠
Vacuolar protein 8
— OG6
C4B63_55g67 ⚠
DNA-directed rna polymerase I largest subunit
— OG6
C4B63_44g236 ⚠
conserved hypothetical protein
— OG6
C4B63_28g152 ⚠
formin-like protein
— OG6
C4B63_9g291 ⚠
conserved hypothetical protein
— OG6
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG6
C4B63_7g1173c ⚠
ubiquitin
— OG6
C4B63_9g446 ⚠
Probable methyltransferase TARBP1
— OG6
C4B63_8g513 ⚠
conserved hypothetical protein
— OG6
C4B63_44g149 ⚠
conserved hypothetical protein
— OG6
C4B63_267g17 ⚠
cullin 4B
— OG6
C4B63_12g314 ⚠
conserved hypothetical protein
— OG6
C4B63_358g1 ⚠
dihydrolipoamide dehydrogenase
— OG6
C4B63_28g153 ⚠
formin-like protein
— OG6
C4B63_57g120 ⚠
Flagellar Member 1
— OG6
C4B63_49g186 ⚠
ccr4-not transcription complex subunit
— OG6
C4B63_19g267 ⚠
Right handed beta helix region containing pro
— OG6
C4B63_6g108 ⚠
DNA replication licensing factor MCM2
— OG6
C4B63_282g10 ⚠
conserved hypothetical protein
— OG6
C4B63_32g232 ⚠
conserved hypothetical protein
— OG6
C4B63_31g220 ⚠
conserved hypothetical protein
— OG6
C4B63_7g395 ⚠
conserved hypothetical protein
— OG6
C4B63_40g87 ⚠
WD40 repeat-containing protein
— OG6
C4B63_81g97 ⚠
conserved hypothetical protein
— OG6
C4B63_267g12 ⚠
conserved hypothetical protein
— OG6
C4B63_19g82 ⚠
RNA polymerase I second largest subunit
— OG6
C4B63_49g173 ⚠
conserved hypothetical protein
— OG6
C4B63_40g106 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG6
C4B63_53g162 ⚠
conserved hypothetical protein
— OG6
C4B63_70g99 ⚠
conserved hypothetical protein
— OG6
C4B63_5g795 ⚠
O-phosphoseryl-tRNA(Sec) selenium transferase
— OG6
C4B63_138g25 ⚠
O-phosphoseryl-tRNA(Sec) selenium transferase
— OG6
C4B63_52g60 ⚠
conserved hypothetical protein
— OG6
C4B63_70g111 ⚠
pumilio-repeat, RNA-binding protein
— OG6
C4B63_70g112 ⚠
pumilio-repeat, RNA-binding protein(fragment)
— OG6
C4B63_45g218 ⚠
conserved hypothetical protein
— OG6
C4B63_45g216 ⚠
conserved hypothetical protein
— OG6
C4B63_45g217 ⚠
WD40 repeat protein
— OG6
C4B63_70g86 ⚠
conserved hypothetical protein
— OG6
C4B63_52g72 ⚠
WD repeat-containing protein 3
— OG6
C4B63_19g266 ⚠
conserved hypothetical protein
— OG6
C4B63_107g4 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG6
C4B63_72g94 ⚠
ribosomal RNA processing protein 40
— OG6
C4B63_7g127 ⚠
conserved hypothetical protein
— OG6
C4B63_6g393 ⚠
conserved hypothetical protein
— OG6
C4B63_282g11 ⚠
conserved hypothetical protein
— OG6
C4B63_20g157 ⚠
NADH dehydrogenase subunit NI8M
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.