C4B63_267g17

cullin 4B
Trypanosoma cruzi Dm28c 2018 OG6: OG6_168578 OG7: OG7_0001577 95 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 95 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_9g291 ⚠
conserved hypothetical protein
— OG6
C4B63_40g156 ⚠
Alkylated DNA repair dioxygenase AlkB
— OG6
C4B63_12g314 ⚠
conserved hypothetical protein
— OG6
C4B63_20g19 ⚠
Nucleoporin
— OG6
C4B63_44g149 ⚠
conserved hypothetical protein
— OG6
C4B63_17g49 ⚠
Pab1p-dependent poly(A) ribonuclease subunit
— OG6
C4B63_48g37 ⚠
conserved hypothetical protein
— OG6
C4B63_7g234 ⚠
Signal recognition particle subunit SRP68
— OG6
C4B63_8g513 ⚠
conserved hypothetical protein
— OG6
C4B63_9g446 ⚠
Probable methyltransferase TARBP1
— OG6
C4B63_7g1173c ⚠
ubiquitin
— OG6
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG6
C4B63_2g91 ⚠
General vesicular transport factor p115
— OG6
C4B63_247g23 ⚠
damage-specific DNA binding protein
— OG6
C4B63_44g236 ⚠
conserved hypothetical protein
— OG6
C4B63_7g87 ⚠
Alpha,alpha-trehalose phosphorylase
— OG6
C4B63_8g209 ⚠
MORN repeat-containing protein 1
— OG6
C4B63_4g128 ⚠
Vacuolar protein 8
— OG6
C4B63_249g23 ⚠
dihydrolipoamide dehydrogenase
— OG6
C4B63_127g51 ⚠
acetyl-CoA carboxylase
— OG6
C4B63_44g129 ⚠
protein phosphatase
— OG6
C4B63_358g1 ⚠
dihydrolipoamide dehydrogenase
— OG6
C4B63_11g100 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG6
C4B63_354g7 ⚠
damage-specific DNA binding protein
— OG6
C4B63_267g12 ⚠
conserved hypothetical protein
— OG6
C4B63_31g109 ⚠
ribose-phosphate pyrophosphokinase
— OG6
C4B63_35g167 ⚠
tubulin tyrosine ligase
— OG6
C4B63_60g127 ⚠
tubulin tyrosine ligase
— OG6
C4B63_60g126 ⚠
tubulin tyrosine ligase
— OG6
C4B63_31g274 ⚠
tubulin tyrosine ligase
— OG6
C4B63_32g232 ⚠
conserved hypothetical protein
— OG6
C4B63_52g72 ⚠
WD repeat-containing protein 3
— OG6
C4B63_16g154 ⚠
exosome component CSL4
— OG6
C4B63_4g200 ⚠
conserved hypothetical protein
— OG6
C4B63_4g201 ⚠
Protein ILITYHIA
— OG6
C4B63_354g8 ⚠
damage-specific DNA binding protein
— OG6
C4B63_19g265 ⚠
F-box protein dre-1
— OG6
C4B63_192g23 ⚠
conserved hypothetical protein
— OG6
C4B63_40g87 ⚠
WD40 repeat-containing protein
— OG6
C4B63_81g97 ⚠
conserved hypothetical protein
— OG6
C4B63_7g395 ⚠
conserved hypothetical protein
— OG6
C4B63_63g93 ⚠
Cell division control protein 48
— OG6
C4B63_19g267 ⚠
Right handed beta helix region containing pro
— OG6
C4B63_282g10 ⚠
conserved hypothetical protein
— OG6
C4B63_6g108 ⚠
DNA replication licensing factor MCM2
— OG6
C4B63_57g120 ⚠
Flagellar Member 1
— OG6
C4B63_18g183 ⚠
damage-specific DNA binding protein
— OG6
C4B63_8g210 ⚠
FYVE zinc-finger
— OG6
C4B63_70g111 ⚠
pumilio-repeat, RNA-binding protein
— OG6
C4B63_28g151 ⚠
formin-like protein
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.