C4B63_2g66

helicase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_146576 OG7: OG7_0000698 116 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 116 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_23g275
ATP-dependent DEAD/H RNA helicase
— OG6
C4B63_3g554 ⚠
NADH-dependent fumarate reductase
— OG6
C4B63_3g551 ⚠
NADH-dependent fumarate reductase
— OG6
C4B63_76g201c
conserved hypothetical protein
— OG6
C4B63_85g64
DNA-damage inducible protein DDI1-like protei
— OG6
C4B63_25g322
U3 small nucleolar RNA-associated protein 25
— OG6
C4B63_25g188
Phosphorylated CTD interacting factor 1 WW do
— OG6
C4B63_23g103
cdc2-related kinase 1
— OG6
C4B63_42g201
conserved hypothetical protein
— OG6
C4B63_51g110
Importin beta-like SAD2
— OG6
C4B63_101g36 ⚠
inositol-3-phosphate synthase
— OG6
C4B63_355g19 ⚠
inositol-3-phosphate synthase(fragment)
— OG6
C4B63_14g147 ⚠
phosphoribosylpyrophosphate synthetase
— OG6
C4B63_2g302
proteasome alpha 1 subunit
— OG6
C4B63_70g86
conserved hypothetical protein
— OG6
C4B63_127g51
acetyl-CoA carboxylase
— OG6
C4B63_206g10 ⚠
acetyltransferase
— OG6
C4B63_43g6 ⚠
T-complex protein 1, delta subunit
— OG6
C4B63_20g172
chaperonin alpha subunit
— OG6
C4B63_59g118
phosphoribosylpyrophosphate synthetase
— OG6
C4B63_2g692
proteasome beta-1 subunit
— OG6
C4B63_70g80
proteasome alpha 7 subunit
— OG6
C4B63_89g44
proteasome beta-1 subunit
— OG6
C4B63_43g135
proteasome alpha 2 subunit
— OG6
C4B63_7g263
ribosomal RNA processing protein 6
— OG6
C4B63_2g380 ⚠
phosphoribosylpyrophosphate synthetase
— OG6
C4B63_47g55
eukaryotic translation initiation factor 5
— OG6
C4B63_112g19
proteasome beta 3 subunit
— OG6
C4B63_49g170 ⚠
ribosomal RNA processing protein 45
— OG6
C4B63_242g4 ⚠
conserved hypothetical protein
— OG6
C4B63_19g113
Translation machinery-associated protein 22
— OG6
C4B63_83g29
ATP-dependent protease ATPase subunit HslU1
— OG6
C4B63_30g129
rrp44p homologue
— OG6
C4B63_11g473
DNL-type zinc finger protein
— OG6
C4B63_12g28
RNA-binding protein
— OG6
C4B63_9g247
small nuclear ribonucleoprotein protein
— OG6
C4B63_10g524
nuclear transcription factor
— OG6
C4B63_93g64 ⚠
amidohydrolase
— OG6
C4B63_93g65 ⚠
amidohydrolase
— OG6
C4B63_122g20 ⚠
ribonucleoside-diphosphate reductase small ch
— OG6
C4B63_27g3 ⚠
ribonucleoside-diphosphate reductase small ch
— OG6
C4B63_34g375 ⚠
Soluble NSF attachment protein, SNAP (parafla
— OG6
C4B63_173g6 ⚠
Soluble NSF attachment protein, SNAP (parafla
— OG6
C4B63_20g12
Vacuolar protein sorting-associated protein 2
— OG6
C4B63_168g37 ⚠
T-complex protein 1, delta subunit
— OG6
C4B63_12g237
eukaryotic release factor 3
— OG6
C4B63_52g137
conserved hypothetical protein
— OG6
C4B63_10g167
conserved hypothetical protein
— OG6
C4B63_4g181
Sestrin-3
— OG6
C4B63_20g197 ⚠
exosome-associated protein 2
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.