C4B63_10g167

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_146709 OG7: OG7_0043725 121 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 121 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_43g129 ⚠
proteasome subunit alpha type-5
— OG7
C4B63_4g477
Probable ATP-dependent RNA helicase DHX35
— Both
C4B63_26g232 ⚠
ubiquitin hydrolase(fragment)
— Both
C4B63_26g231 ⚠
ubiquitin hydrolase(fragment)
— Both
C4B63_2g66
helicase
— OG6
C4B63_18g223
eukaryotic translation initiation factor 3 su
— Both
C4B63_127g51
acetyl-CoA carboxylase
— Both
C4B63_22g82
conserved hypothetical protein
— Both
C4B63_69g156
conserved hypothetical protein
— Both
C4B63_31g178 ⚠
Zinc phosphodiesterase ELAC protein 2
— Both
C4B63_31g177 ⚠
ribonuclease Z
— Both
C4B63_112g19
proteasome beta 3 subunit
— Both
C4B63_85g46 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
C4B63_12g1641c ⚠
DNA-directed RNA polymerase I subunit RPB10
— Both
C4B63_46g417c ⚠
DNA-directed RNA polymerase I subunit
— Both
C4B63_267g91c ⚠
DNA-directed RNA polymerase I subunit RPB10
— Both
C4B63_70g80 ⚠
proteasome alpha 7 subunit
— Both
C4B63_7g124 ⚠
conserved hypothetical protein
— OG7
C4B63_21g267 ⚠
conserved hypothetical protein
— OG7
C4B63_21g269 ⚠
conserved hypothetical protein
— OG7
C4B63_21g274 ⚠
conserved hypothetical protein
— OG7
C4B63_21g272 ⚠
conserved hypothetical protein
— OG7
C4B63_22g108 ⚠
Replication Factor C Subunit 1-related protei
— OG7
C4B63_2g762 ⚠
replication factor C, subunit 3
— OG7
C4B63_61g82 ⚠
Chromosome transmission fidelity protein 18 h
— OG7
C4B63_28g129 ⚠
replication factor C, subunit 1
— OG7
C4B63_18g277 ⚠
replication factor C, subunit 2
— OG7
C4B63_61g81 ⚠
conserved hypothetical protein
— OG7
C4B63_63g41 ⚠
replication factor C, subunit 3
— OG7
C4B63_39g340 ⚠
replication factor C, subunit 4
— OG7
C4B63_7g98 ⚠
Eukaryotic translation initiation factor 2-al
— OG7
C4B63_6g384 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
C4B63_6g268 ⚠
conserved hypothetical protein
— OG7
C4B63_330g11 ⚠
conserved hypothetical protein
— OG7
C4B63_218g25 ⚠
conserved hypothetical protein
— OG7
C4B63_17g55 ⚠
cyclin 9
— OG7
C4B63_2g46 ⚠
conserved hypothetical protein
— OG7
C4B63_2g47 ⚠
conserved hypothetical protein
— OG7
C4B63_161g30 ⚠
conserved hypothetical protein
— OG7
C4B63_7g290 ⚠
RING finger protein ETP1
— OG7
C4B63_233g31 ⚠
ubiquitin hydrolase
— OG7
C4B63_233g32 ⚠
ubiquitin hydrolase
— OG7
C4B63_7g392 ⚠
ubiquitin hydrolase
— OG7
C4B63_7g391 ⚠
ubiquitin hydrolase
— OG7
C4B63_2g4 ⚠
ubiquitin hydrolase
— OG7
C4B63_45g221 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_21g245 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_57g94 ⚠
ATP-dependent RNA helicase
— OG7
C4B63_48g131 ⚠
proteasome subunit beta type-5
— OG7
C4B63_4g427 ⚠
RNA-binding protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.