C4B63_85g64

DNA-damage inducible protein DDI1-like protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101685 OG7: OG7_0006273 231 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 231 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_70g129 ⚠
metallo-peptidase, Clan MF, Family M17
— +3 more Both
C4B63_12g153 ⚠
metallo-peptidase, Clan MF, Family M17
— +3 more Both
C4B63_193g9 ⚠
metallo-peptidase, Clan MF, Family M17
— +3 more Both
C4B63_2g450 ⚠
metallo-peptidase, Clan MF, Family M17
— +1 more Both
C4B63_19g179
protein kinase
— OG7
C4B63_101g15
serine peptidase, Clan SC, Family S9B
— Both
C4B63_56g32 ⚠
GTPase
— OG7
C4B63_181g13 ⚠
conserved hypothetical protein
— OG7
C4B63_20g49
conserved hypothetical protein
— OG7
C4B63_171g30 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
C4B63_243g9 ⚠
CYC2-like cyclin
— OG7
C4B63_114g1 ⚠
N-acetyltransferase
— OG7
C4B63_157g28 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
C4B63_6g521 ⚠
DIS3-like exonuclease
— OG7
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_2g345 ⚠
GTP-binding protein
— OG7
C4B63_91g35 ⚠
GTPase
— OG7
C4B63_34g156 ⚠
Acyl-CoA-binding domain-containing protein 4
— OG7
C4B63_8g202 ⚠
GTP-binding protein
— OG7
C4B63_25g968c ⚠
Acyl-CoA-binding domain-containing protein 5
— OG7
C4B63_206g3 ⚠
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminoc
— OG7
C4B63_297g7 ⚠
CYC2-like cyclin(fragment)
— OG7
C4B63_83g79 ⚠
RNA pseudouridylate synthase
— OG7
C4B63_44g117
conserved hypothetical protein
— OG7
C4B63_49g325c ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
C4B63_14g19 ⚠
flagellum transition zone component
— OG7
C4B63_23g116 ⚠
Importin beta-like SAD2
— OG7
C4B63_47g96 ⚠
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminoc
— OG7
C4B63_13g160 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
C4B63_32g238 ⚠
tubulin folding cofactor D
— Both
C4B63_32g239 ⚠
tubulin folding cofactor D
— Both
C4B63_42g187
conserved hypothetical protein
— Both
C4B63_227g4 ⚠
Zinc finger protein 474
— Both
C4B63_133g51
heat shock protein 70
— OG7
C4B63_22g161 ⚠
calpain-like cysteine peptidase
— OG6
C4B63_4g269
conserved hypothetical protein
— Both
C4B63_43g143 ⚠
protein kinase
— Both
C4B63_7g77
conserved hypothetical protein
— Both
C4B63_3g1104
threonyl-tRNA synthetase
— Both
C4B63_297g14 ⚠
phenylalanyl-tRNA synthetase alpha chain
— Both
C4B63_7g395
conserved hypothetical protein
— Both
C4B63_47g49 ⚠
tRNA pseudouridine synthase 1
— Both
C4B63_153g41 ⚠
inositol 5-phosphatase 1(fragment)
— Both
C4B63_21g30 ⚠
Exportin-7-A
— Both
C4B63_7g417
snoRNP protein GAR1
— Both
C4B63_27g4 ⚠
ubiquitin ligase
— Both
C4B63_2g748
conserved hypothetical protein
— Both
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.