C4B63_3g1104

threonyl-tRNA synthetase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100294 OG7: OG7_0003264 130 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 130 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_7g79 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_41g128 ⚠
conserved hypothetical protein
— OG7
C4B63_224g16 ⚠
conserved hypothetical protein
— OG7
C4B63_41g122 ⚠
conserved hypothetical protein
— OG7
C4B63_41g125 ⚠
conserved hypothetical protein
— OG7
C4B63_41g119 ⚠
conserved hypothetical protein
— OG7
C4B63_2g376 ⚠
ribosome assembly protein RRB1
— Both
C4B63_22g22 ⚠
ARM-like helical domain-containing protein
— Both
C4B63_80g25 ⚠
ubiquitin hydrolase
— Both
C4B63_42g49
Protein aardvark
— Both
C4B63_17g253
Paraflagellar Rod Proteome Component 9
— Both
C4B63_57g75 ⚠
dihydrolipoamide acetyltransferase precursor
— Both
C4B63_83g73
ribonucleoprotein p18, mitochondrial precurso
— Both
C4B63_85g64
DNA-damage inducible protein DDI1-like protei
— Both
C4B63_32g256 ⚠
PFU (PLAA family ubiquitin binding)
— Both
C4B63_32g255 ⚠
WD domain, G-beta repeat
— Both
C4B63_4g116
FACT complex subunit ssrp1-B
— Both
C4B63_160g6 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_16g30 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_63g95 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_22g11 ⚠
developmentally regulated phosphoprotein
— Both
C4B63_24g190 ⚠
Exportin-7
— Both
C4B63_21g30 ⚠
Exportin-7-A
— Both
C4B63_11g484
Leucine Rich Repeat protein
— Both
C4B63_23g248 ⚠
inorganic pyrophosphatase
— Both
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— Both
C4B63_54g57
vacuolar ATP synthase subunit d
— Both
C4B63_14g155
Leucine-rich repeat-containing protein 74A
— Both
C4B63_122g21 ⚠
ubiquitin ligase
— Both
C4B63_27g4 ⚠
ubiquitin ligase
— Both
C4B63_26g261 ⚠
glutamate dehydrogenase
— Both
C4B63_39g329
glycyl-tRNA synthetase
— Both
C4B63_295g26 ⚠
glutamate dehydrogenase
— Both
C4B63_42g187
conserved hypothetical protein
— Both
C4B63_13g257 ⚠
endonuclease/exonuclease/phosphatase
— OG7
C4B63_2g502 ⚠
ubiquitin carboxyl-terminal hydrolase
— OG7
C4B63_252g9 ⚠
ubiquitin carboxyl-terminal hydrolase
— OG7
C4B63_7g377 ⚠
[Pyruvate dehydrogenase (acetyl-transferring)
— OG7
C4B63_14g103 ⚠
beta adaptin
— OG7
C4B63_40g106 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
C4B63_12g219 ⚠
adaptin-related protein-like
— OG7
C4B63_20g38 ⚠
Synaptojanin
— OG7
C4B63_396g8 ⚠
synaptojanin (N-terminal domain)
— OG7
C4B63_28g111 ⚠
synaptojanin
— OG7
C4B63_85g75 ⚠
ubiquitin activating enzyme
— OG7
C4B63_2g83 ⚠
ubiquitin hydrolase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.