C4B63_12g153

metallo-peptidase, Clan MF, Family M17
Trypanosoma cruzi Dm28c 2018 OG6: OG6_142599 OG7: OG7_0003405 340 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 340 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_93g64 ⚠
amidohydrolase
— +9 more Both
C4B63_93g65 ⚠
amidohydrolase
— +9 more Both
C4B63_30g129 ⚠
rrp44p homologue
— +2 more Both
C4B63_42g187 ⚠
conserved hypothetical protein
— Both
C4B63_3g550 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_14g97 ⚠
isoleucyl-tRNA synthetase
— Both
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_54g71 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_6g521 ⚠
DIS3-like exonuclease
— OG7
C4B63_15g19 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_38g169 ⚠
calpain-like cysteine peptidase
— OG6
C4B63_42g49 ⚠
Protein aardvark
— Both
C4B63_54g70 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_31g99 ⚠
WD repeat-containing protein 17
— Both
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_3g553 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_14g96 ⚠
isoleucil-tRNA synthetase
— Both
C4B63_22g164 ⚠
calpain-like cysteine peptidase
— OG6
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_22g161 ⚠
calpain-like cysteine peptidase
— OG6
C4B63_85g64 ⚠
DNA-damage inducible protein DDI1-like protei
— +3 more Both
C4B63_40g52 ⚠
conserved hypothetical protein
— +2 more Both
C4B63_15g18 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_3g551 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_3g554 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_3g552 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_7g79 ⚠
aspartyl-tRNA synthetase
— +1 more Both
C4B63_297g7 ⚠
CYC2-like cyclin(fragment)
— OG7
C4B63_25g968c ⚠
Acyl-CoA-binding domain-containing protein 5
— OG7
C4B63_34g156 ⚠
Acyl-CoA-binding domain-containing protein 4
— OG7
C4B63_7g1820c ⚠
acyl-CoA binding protein
— OG7
C4B63_109g69 ⚠
Acyl-CoA-binding domain-containing protein 4
— OG7
C4B63_61g73 ⚠
Acyl-CoA-binding domain-containing protein 5
— OG7
C4B63_47g96 ⚠
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminoc
— OG7
C4B63_359g9 ⚠
conserved hypothetical protein
— OG7
C4B63_26g232 ⚠
ubiquitin hydrolase(fragment)
— OG7
C4B63_14g19 ⚠
flagellum transition zone component
— OG7
C4B63_2g4 ⚠
ubiquitin hydrolase
— OG7
C4B63_48g124 ⚠
neurobeachin/beige protein
— OG7
C4B63_243g9 ⚠
CYC2-like cyclin
— OG7
C4B63_54g62 ⚠
proteasome activator protein pa26
— OG7
C4B63_92g114 ⚠
conserved hypothetical protein
— OG7
C4B63_2g817 ⚠
conserved hypothetical protein
— OG7
C4B63_157g28 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
C4B63_114g1 ⚠
N-acetyltransferase
— OG7
C4B63_171g30 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
C4B63_293g30c ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.