C4B63_2g345

GTP-binding protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101533 OG7: OG7_0001608 260 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 260 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_350g11 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_233g31 ⚠
ubiquitin hydrolase
— OG7
C4B63_233g32 ⚠
ubiquitin hydrolase
— OG7
C4B63_13g118 ⚠
tRNA-dihydrouridine synthase 2
— OG7
C4B63_20g51 ⚠
tRNA-dihydrouridine synthase 4
— OG7
C4B63_336g10 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_109g69 ⚠
Acyl-CoA-binding domain-containing protein 4
— OG7
C4B63_122g18 ⚠
acyl-CoA binding protein
— OG7
C4B63_7g1820c ⚠
acyl-CoA binding protein
— OG7
C4B63_134g60 ⚠
aspartate carbamoyltransferase
— OG7
C4B63_51g180 ⚠
N-acetyltransferase complex ARD1 subunit
— OG7
C4B63_134g73 ⚠
conserved hypothetical protein
— OG7
C4B63_60g125 ⚠
XRN 5'-3' exonuclease N-terminus
— OG7
C4B63_32g259 ⚠
Cyclin-U4-1
— OG7
C4B63_293g2 ⚠
p22 protein precursor (Mitochondrial glycopro
— OG7
C4B63_2g567 ⚠
mRNA export factor MEX67
— OG7
C4B63_72g98 ⚠
RNA pseudouridylate synthase protein
— OG7
C4B63_18g219 ⚠
tRNA methyltransferase 10 homolog A
— OG7
C4B63_13g1005c ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
C4B63_293g30c ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
C4B63_4g509 ⚠
FKBP-type peptidylprolyl cis-trans isomerase
— OG7
C4B63_93g64 ⚠
amidohydrolase
— OG7
C4B63_12g153 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_313g3 ⚠
dihydrouridine synthase (Dus)(fragment)
— OG7
C4B63_35g155 ⚠
aspartate carbamoyltransferase
— OG7
C4B63_51g110 ⚠
Importin beta-like SAD2
— OG7
C4B63_18g174 ⚠
cyclin
— OG7
C4B63_56g69 ⚠
CYC2-like cyclin
— OG7
C4B63_2g88 ⚠
ubiquitin-protein ligase
— OG7
C4B63_7g382 ⚠
ubiquitin-protein ligase
— OG7
C4B63_2g786 ⚠
ubiquitin-activating enzyme E1
— OG7
C4B63_7g392 ⚠
ubiquitin hydrolase
— OG7
C4B63_70g129 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_134g71 ⚠
conserved hypothetical protein
— OG7
C4B63_60g116 ⚠
aspartate carbamoyltransferase
— OG7
C4B63_2g761 ⚠
Peroxin 19
— OG7
C4B63_49g54 ⚠
p22 protein precursor (Mitochondrial glycopro
— OG7
C4B63_243g9 ⚠
CYC2-like cyclin
— OG7
C4B63_25g257 ⚠
zinc-finger protein ZPR1
— OG7
C4B63_339g3 ⚠
tRNA-dihydrouridine synthase 3
— OG7
C4B63_171g30 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
C4B63_20g49 ⚠
conserved hypothetical protein
— OG7
C4B63_13g152 ⚠
elongation factor 2
— OG7
C4B63_18g217 ⚠
homoserine kinase
— OG7
C4B63_20g61 ⚠
conserved hypothetical protein
— OG7
C4B63_181g13 ⚠
conserved hypothetical protein
— OG7
C4B63_13g157 ⚠
elongation factor 2
— OG7
C4B63_13g153 ⚠
elongation factor 2
— OG7
C4B63_11g473 ⚠
DNL-type zinc finger protein
— OG7
C4B63_42g70 ⚠
p22 protein precursor
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.