C4B63_60g116

aspartate carbamoyltransferase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_103175 OG7: OG7_0002367 133 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 133 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_11g17 ⚠
translation elongation factor EF-2
— Both
C4B63_13g156 ⚠
elongation factor 2
— Both
C4B63_13g153 ⚠
elongation factor 2
— Both
C4B63_13g157 ⚠
elongation factor 2
— Both
C4B63_13g152 ⚠
elongation factor 2
— Both
C4B63_13g155 ⚠
elongation factor 2
— Both
C4B63_13g154 ⚠
elongation factor 2
— Both
C4B63_11g18 ⚠
translation elongation factor EF-2
— Both
C4B63_9g523 ⚠
U5 small nuclear ribonucleoprotein component
— OG7
C4B63_170g15 ⚠
aminopeptidase
— OG7
C4B63_21g261 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
C4B63_14g183 ⚠
mitochondrial intermediate peptidase
— OG7
C4B63_7g236 ⚠
regulatory subunit of protein kinase a-like p
— OG7
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
C4B63_2g431 ⚠
GTPase protein
— OG7
C4B63_2g345 ⚠
GTP-binding protein
— OG7
C4B63_4g324 ⚠
aconitase
— Both
C4B63_62g82 ⚠
thimet oligopeptidase
— Both
C4B63_37g366 ⚠
thimet oligopeptidase
— Both
C4B63_147g45 ⚠
kynureninase
— Both
C4B63_16g302 ⚠
3-ketoacyl-CoA thiolase
— Both
C4B63_18g204 ⚠
3-hydroxy-3-methylglutaryl-CoA reductase
— Both
C4B63_32g225 ⚠
3-hydroxy-3-methylglutaryl-CoA synthase
— Both
C4B63_56g86 ⚠
methylthioadenosine phosphorylase
— Both
C4B63_2g752 ⚠
6-phosphogluconate dehydrogenase, decarboxyla
— Both
C4B63_24g246 ⚠
kynureninase
— Both
C4B63_23g83 ⚠
Aminopeptidase M1
— Both
C4B63_6g113 ⚠
ribonucleoside-diphosphate reductase large ch
— Both
C4B63_51g192 ⚠
protein kinase A regulatory subunit
— Both
C4B63_32g236 ⚠
transketolase
— Both
C4B63_69g59 ⚠
conserved hypothetical protein
— Both
C4B63_144g28 ⚠
conserved hypothetical protein
— Both
C4B63_34g313 ⚠
casein kinase II, alpha chain
— OG6
C4B63_80g21 ⚠
Nucleoside diphosphate kinase
— Both
C4B63_13g352 ⚠
cytosolic nonspecific dipeptidase
— Both
C4B63_22g59 ⚠
cytidine triphosphate synthase
— Both
C4B63_113g58 ⚠
hydrogenase
— Both
C4B63_46g74 ⚠
aminopeptidase
— OG7
C4B63_41g246 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
C4B63_41g245 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
C4B63_233g32 ⚠
ubiquitin hydrolase
— OG7
C4B63_56g82 ⚠
mitochondrial glycoprotein-like protein
— OG7
C4B63_7g382 ⚠
ubiquitin-protein ligase
— OG7
C4B63_293g2 ⚠
p22 protein precursor (Mitochondrial glycopro
— OG7
C4B63_60g125 ⚠
XRN 5'-3' exonuclease N-terminus
— OG7
C4B63_134g73 ⚠
conserved hypothetical protein
— OG7
C4B63_20g51 ⚠
tRNA-dihydrouridine synthase 4
— OG7
C4B63_13g118 ⚠
tRNA-dihydrouridine synthase 2
— OG7
C4B63_10g137 ⚠
conserved hypothetical protein
— OG7
C4B63_8g202 ⚠
GTP-binding protein
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.