C4B63_32g236

transketolase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100329 OG7: OG7_0003500 78 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 78 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_35g155 ⚠
aspartate carbamoyltransferase
— Both
C4B63_220g12 ⚠
peroxidoxin
— Both
C4B63_18g164
S-adenosylmethionine synthetase
— Both
C4B63_114g23
UBX domain-containing protein 3
— Both
C4B63_36g68 ⚠
mucin TcMUCII
— OG6
C4B63_32g217 ⚠
2-amino-3-ketobutyrate coenzyme A ligase
— Both
C4B63_32g214 ⚠
2-amino-3-ketobutyrate coenzyme A ligase
— Both
C4B63_227g20 ⚠
pyruvate kinase 2
— Both
C4B63_4g146 ⚠
pyruvate kinase 2
— Both
C4B63_134g60 ⚠
aspartate carbamoyltransferase
— Both
C4B63_295g16 ⚠
tryparedoxin peroxidase
— Both
C4B63_60g116 ⚠
aspartate carbamoyltransferase
— Both
C4B63_31g264 ⚠
aspartate carbamoyltransferase
— Both
C4B63_20g6 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— +2 more Both
C4B63_23g211 ⚠
protein kinase(fragment)
— OG6
C4B63_11g8
succinyl-CoA synthetase alpha subunit
— Both
C4B63_7g161 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— +2 more Both
C4B63_7g169 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— +2 more Both
C4B63_7g173 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— +2 more Both
C4B63_133g46
cytosolic malate dehydrogenase
— Both
C4B63_28g60 ⚠
fumarate hydratase
— Both
C4B63_14g183 ⚠
mitochondrial intermediate peptidase
— OG7
C4B63_7g356 ⚠
serine-palmitoyl-CoA transferase
— OG7
C4B63_54g18 ⚠
serine palmitoyltransferase
— OG7
C4B63_18g130 ⚠
glutamyl-tRNA synthetase
— OG7
C4B63_7g430 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
C4B63_7g236 ⚠
regulatory subunit of protein kinase a-like p
— OG7
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
C4B63_248g14 ⚠
glucose-6-phosphate isomerase, glycosomal
— Both
C4B63_41g194 ⚠
glucose-6-phosphate isomerase, glycosomal
— Both
C4B63_7g157 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— +2 more Both
C4B63_23g130 ⚠
Fumarate hydratase class I, cytosolic
— Both
C4B63_295g20 ⚠
tryparedoxin peroxidase
— Both
C4B63_26g253 ⚠
tryparedoxin peroxidase
— Both
C4B63_149g19 ⚠
peroxidoxin
— Both
C4B63_26g255 ⚠
tryparedoxin peroxidase
— Both
C4B63_26g257 ⚠
tryparedoxin peroxidase
— Both
C4B63_295g22 ⚠
tryparedoxin peroxidase
— Both
C4B63_295g18 ⚠
tryparedoxin peroxidase
— Both
C4B63_150g38 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_85g55 ⚠
fatty acyl CoA syntetase 1
— Both
C4B63_206g21 ⚠
fatty acyl CoA synthetase
— Both
C4B63_26g206 ⚠
glutaminyl-tRNA synthetase
— Both
C4B63_85g54 ⚠
fatty acyl CoA synthetase 2
— Both
C4B63_2g292 ⚠
glyceraldehyde-3-phosphate dehydrogenase
— OG6
C4B63_86g56 ⚠
glyceraldehyde-3-phosphate dehydrogenase
— OG6
C4B63_47g115 ⚠
fatty acyl CoA synthetase
— Both
C4B63_85g53 ⚠
fatty acyl CoA synthetase 2
— Both
C4B63_18g232 ⚠
glyceraldehyde 3-phosphate dehydrogenase
— OG6
C4B63_85g51 ⚠
fatty acyl CoA syntetase 1
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.