C4B63_2g292

glyceraldehyde-3-phosphate dehydrogenase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_177235 OG7: OG7_0002325 50 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 50 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_101g15 ⚠
serine peptidase, Clan SC, Family S9B
— OG6
C4B63_82g71 ⚠
tryptophanyl-tRNA synthetase
— OG6
C4B63_10g517 ⚠
tryptophanyl-tRNA synthetase
— OG6
C4B63_8g41 ⚠
RNA-binding protein
— OG6
C4B63_85g54 ⚠
fatty acyl CoA synthetase 2
— OG6
C4B63_20g170 ⚠
glucosamine-6-phosphate isomerase
— OG6
C4B63_85g53 ⚠
fatty acyl CoA synthetase 2
— OG6
C4B63_47g115 ⚠
fatty acyl CoA synthetase
— OG6
C4B63_206g21 ⚠
fatty acyl CoA synthetase
— OG6
C4B63_85g55 ⚠
fatty acyl CoA syntetase 1
— OG6
C4B63_85g51 ⚠
fatty acyl CoA syntetase 1
— OG6
C4B63_348g24 ⚠
guanine deaminase
— OG6
C4B63_10g404 ⚠
guanine deaminase
— OG6
C4B63_4g500 ⚠
GDP-mannose 4,6 dehydratase
— OG6
C4B63_4g146 ⚠
pyruvate kinase 2
— OG6
C4B63_227g20 ⚠
pyruvate kinase 2
— OG6
C4B63_7g391 ⚠
ubiquitin hydrolase
— OG6
C4B63_7g392 ⚠
ubiquitin hydrolase
— OG6
C4B63_18g164 ⚠
S-adenosylmethionine synthetase
— OG6
C4B63_23g130 ⚠
Fumarate hydratase class I, cytosolic
— OG6
C4B63_28g60 ⚠
fumarate hydratase
— OG6
C4B63_16g160 ⚠
GAF domain/TIP41-like family
— OG6
C4B63_6g433 ⚠
conserved hypothetical protein
— OG6
C4B63_41g194 ⚠
glucose-6-phosphate isomerase, glycosomal
— OG6
C4B63_248g14 ⚠
glucose-6-phosphate isomerase, glycosomal
— OG6
C4B63_26g206 ⚠
glutaminyl-tRNA synthetase
— OG6
C4B63_170g28 ⚠
adenylosuccinate synthetase
— OG6
C4B63_23g131 ⚠
protein farnesyltransferase alpha subunit
— OG6
C4B63_37g364 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_18g233 ⚠
glyceraldehyde 3-phosphate dehydrogenase
— OG6
C4B63_8g249 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_81g63 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_50g7 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_8g221 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_26g353 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_57g67 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_150g38 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_18g232 ⚠
glyceraldehyde 3-phosphate dehydrogenase
— OG6
C4B63_46g82 ⚠
adenylosuccinate synthetase
— OG6
C4B63_9g270 ⚠
GTP-binding protein
— OG6
C4B63_32g236 ⚠
transketolase
— OG6
C4B63_26g205 ⚠
proliferative cell nuclear antigen (PCNA)
— OG6
C4B63_31g48 ⚠
queuine tRNA-ribosyltransferase
— OG6
C4B63_19g45 ⚠
isovaleryl-coA dehydrogenase
— OG6
C4B63_25g288 ⚠
inosine-guanine nucleoside hydrolase
— OG6
C4B63_63g30 ⚠
Histone-lysine N-methyltransferase ATXR2
— OG6
C4B63_19g245 ⚠
conserved hypothetical protein
— OG6
C4B63_70g67 ⚠
NGG1 interacting factor 3
— OG6
C4B63_4g513 ⚠
Target of rapamycin complex subunit LST8
— OG6
C4B63_4g497 ⚠
GDP-mannose 4,6 dehydratase
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.