C4B63_23g131

protein farnesyltransferase alpha subunit
Trypanosoma cruzi Dm28c 2018 OG6: OG6_151900 OG7: OG7_0052100 74 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 74 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_259g22 ⚠
Ring finger domain containing protein
— OG6
C4B63_69g61 ⚠
Kinesin-13 1
— OG7
C4B63_44g235 ⚠
Kinesin-13 4
— OG7
C4B63_144g30 ⚠
Kinesin-13 1
— OG7
C4B63_42g42
co-chaperone GrpE
— Both
C4B63_6g205 ⚠
Mitochondrial import receptor subunit ATOM69
— Both
C4B63_230g12 ⚠
Mitochondrial import receptor subunit ATOM69
— Both
C4B63_16g160
GAF domain/TIP41-like family
— Both
C4B63_34g118 ⚠
conserved hypothetical protein
— Both
C4B63_109g37 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
C4B63_325g1 ⚠
Kinesin-13 1
— OG7
C4B63_16g147 ⚠
Ring finger domain containing protein
— OG6
C4B63_8g219 ⚠
protein farnesyltransferase
— Both
C4B63_50g5 ⚠
protein farnesyltransferase
— Both
C4B63_20g357
Carnosine N-methyltransferase
— Both
C4B63_7g392 ⚠
ubiquitin hydrolase
— Both
C4B63_7g391 ⚠
ubiquitin hydrolase
— Both
C4B63_163g28
conserved hypothetical protein
— Both
C4B63_212g12 ⚠
anion-transporting ATPase-like
— Both
C4B63_233g31 ⚠
ubiquitin hydrolase
— OG7
C4B63_206g3 ⚠
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminoc
— OG7
C4B63_47g96 ⚠
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminoc
— OG7
C4B63_6g517 ⚠
geranylgeranyl transferase type II beta subun
— OG7
C4B63_7g388 ⚠
geranylgeranyl transferase type II beta subun
— OG7
C4B63_10g489 ⚠
ADP-ribosylation factor GTPase activating pro
— OG7
C4B63_6g417 ⚠
ADP-ribosylation factor GTPase activating pro
— OG7
C4B63_75g70 ⚠
ADP-ribosylation factor GTPase activating pro
— OG7
C4B63_17g265 ⚠
Probable ADP-ribosylation factor GTPase-activ
— OG7
C4B63_12g179 ⚠
anion-transporting ATPase-like
— Both
C4B63_233g32 ⚠
ubiquitin hydrolase
— OG7
C4B63_26g231 ⚠
ubiquitin hydrolase(fragment)
— OG7
C4B63_2g4 ⚠
ubiquitin hydrolase
— OG7
C4B63_26g232 ⚠
ubiquitin hydrolase(fragment)
— OG7
C4B63_2g75 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_30g132 ⚠
ubiquitin activating enzyme
— OG7
C4B63_2g74 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_46g15 ⚠
Kinesin-13 5
— OG7
C4B63_19g245
conserved hypothetical protein
— Both
C4B63_12g310 ⚠
Structure-specific endonuclease subunit SLX1
— Both
C4B63_2g417 ⚠
conserved hypothetical protein
— Both
C4B63_267g7 ⚠
GIY-YIG catalytic domain containing protein
— Both
C4B63_267g8 ⚠
Structure-specific endonuclease subunit SLX1
— Both
C4B63_25g232
Tetratricopeptide repeat protein 27 homolog
— Both
C4B63_26g305 ⚠
conserved hypothetical protein
— Both
C4B63_2g292 ⚠
glyceraldehyde-3-phosphate dehydrogenase
— OG6
C4B63_86g56 ⚠
glyceraldehyde-3-phosphate dehydrogenase
— OG6
C4B63_2g416 ⚠
conserved hypothetical protein
— Both
C4B63_18g68
Zinc finger protein 277
— Both
C4B63_23g76
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_26g306 ⚠
conserved hypothetical protein
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.