C4B63_18g68

Zinc finger protein 277
Trypanosoma cruzi Dm28c 2018 OG6: OG6_104708 OG7: OG7_0037644 62 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 62 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_30g132 ⚠
ubiquitin activating enzyme
— OG7
C4B63_168g23 ⚠
Programmed cell death protein 2, C-terminal d
— Both
C4B63_6g411
Replication factor A 51 kDa subunit
— Both
C4B63_102g71 ⚠
Programmed cell death protein 2, C-terminal d
— Both
C4B63_16g122 ⚠
Beta-lactamase superfamily domain containing
— Both
C4B63_49g131 ⚠
conserved hypothetical protein
— Both
C4B63_49g130 ⚠
Putative hydrolase C777.06c
— Both
C4B63_16g147 ⚠
Ring finger domain containing protein
— OG6
C4B63_259g22 ⚠
Ring finger domain containing protein
— OG6
C4B63_109g37 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
C4B63_34g118 ⚠
conserved hypothetical protein
— Both
C4B63_144g30 ⚠
Kinesin-13 1
— OG7
C4B63_44g235 ⚠
Kinesin-13 4
— OG7
C4B63_69g61 ⚠
Kinesin-13 1
— OG7
C4B63_325g1 ⚠
Kinesin-13 1
— OG7
C4B63_46g15 ⚠
Kinesin-13 5
— OG7
C4B63_34g313
casein kinase II, alpha chain
— OG6
C4B63_21g114 ⚠
oxidoreductase
— OG7
C4B63_199g21 ⚠
oxidoreductase
— OG7
C4B63_24g224
conserved hypothetical protein
— OG7
C4B63_21g280
ribonuclease mar1
— OG7
C4B63_61g23 ⚠
tRNA-dihydrouridine synthase 3
— OG7
C4B63_339g3 ⚠
tRNA-dihydrouridine synthase 3
— OG7
C4B63_20g51 ⚠
tRNA-dihydrouridine synthase 4
— OG7
C4B63_13g118 ⚠
tRNA-dihydrouridine synthase 2
— OG7
C4B63_7g323 ⚠
conserved hypothetical protein
— OG7
C4B63_7g324 ⚠
Programmed cell death protein 2, C-terminal d
— OG7
C4B63_263g16 ⚠
Programmed cell death protein 2-like
— OG7
C4B63_19g271
conserved hypothetical protein
— OG7
C4B63_47g96 ⚠
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminoc
— OG7
C4B63_206g3 ⚠
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminoc
— OG7
C4B63_336g10 ⚠
dihydrouridine synthase (Dus)
— Both
C4B63_20g55
Ribosome maturation protein SBDS
— Both
C4B63_18g222
Ubiquitin carboxyl-terminal hydrolase MINDY-1
— Both
C4B63_9g308 ⚠
ubiquitin activating enzyme
— Both
C4B63_32g18
protein kinase
— OG6
C4B63_170g16 ⚠
Thiamin pyrophosphokinase 1
— Both
C4B63_46g75 ⚠
Thiamin pyrophosphokinase 1
— Both
C4B63_42g192
N-alpha-acetyltransferase 25, NatB auxiliary
— Both
C4B63_6g389
D123
— Both
C4B63_18g157
DNA ligase I
— Both
C4B63_13g352
cytosolic nonspecific dipeptidase
— Both
C4B63_322g8 ⚠
dihydrouridine synthase (Dus)
— Both
C4B63_9g390
tyrosyl-DNA Phosphodiesterase (Tdp1)
— Both
C4B63_294g17 ⚠
dihydrouridine synthase (Dus)
— Both
C4B63_350g11 ⚠
dihydrouridine synthase (Dus)
— Both
C4B63_313g3 ⚠
dihydrouridine synthase (Dus)(fragment)
— Both
C4B63_23g131
protein farnesyltransferase alpha subunit
— Both
C4B63_294g18 ⚠
dihydrouridine synthase (Dus)
— Both
C4B63_28g91 ⚠
Kinesin-13 3
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.