C4B63_263g16

Programmed cell death protein 2-like
Trypanosoma cruzi Dm28c 2018 OG6: OG6_136955 OG7: OG7_0004545 89 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 89 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_87g16 ⚠
pitrilysin-like metalloprotease
— OG7
C4B63_87g17 ⚠
pitrilysin-like metalloprotease
— OG7
C4B63_20g51 ⚠
tRNA-dihydrouridine synthase 4
— OG7
C4B63_13g118 ⚠
tRNA-dihydrouridine synthase 2
— OG7
C4B63_336g10 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_313g3 ⚠
dihydrouridine synthase (Dus)(fragment)
— OG7
C4B63_18g68 ⚠
Zinc finger protein 277
— OG7
C4B63_2g786 ⚠
ubiquitin-activating enzyme E1
— OG7
C4B63_350g11 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_322g8 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_13g352 ⚠
cytosolic nonspecific dipeptidase
— OG7
C4B63_19g271 ⚠
conserved hypothetical protein
— OG7
C4B63_339g3 ⚠
tRNA-dihydrouridine synthase 3
— OG7
C4B63_16g122 ⚠
Beta-lactamase superfamily domain containing
— OG7
C4B63_18g157 ⚠
DNA ligase I
— OG7
C4B63_6g411 ⚠
Replication factor A 51 kDa subunit
— OG7
C4B63_16g331 ⚠
ubiquitin-activating enzyme E1
— OG7
C4B63_6g389 ⚠
D123
— OG7
C4B63_61g23 ⚠
tRNA-dihydrouridine synthase 3
— OG7
C4B63_294g17 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_9g390 ⚠
tyrosyl-DNA Phosphodiesterase (Tdp1)
— OG7
C4B63_9g323 ⚠
conserved hypothetical protein
— OG7
C4B63_46g75 ⚠
Thiamin pyrophosphokinase 1
— OG7
C4B63_51g96 ⚠
UPF0301 protein BT 1078
— OG7
C4B63_48g163 ⚠
ARF-like 2 binding protein BART
— OG7
C4B63_44g214 ⚠
conserved hypothetical protein
— OG7
C4B63_148g30 ⚠
conserved hypothetical protein
— OG7
C4B63_17g239 ⚠
conserved hypothetical protein
— OG7
C4B63_11g71 ⚠
conserved hypothetical protein
— OG7
C4B63_4g235 ⚠
5-oxoprolinase
— OG7
C4B63_4g234 ⚠
5-oxoprolinase
— OG7
C4B63_10g125 ⚠
ankyrin
— OG7
C4B63_4g244 ⚠
ankyrin repeat family protein
— OG7
C4B63_56g58 ⚠
ankyrin,
— OG7
C4B63_2g828 ⚠
ankyrin repeat protein
— OG7
C4B63_32g22 ⚠
Uncharacterized WD repeat-containing protein
— OG7
C4B63_2g70 ⚠
conserved hypothetical protein
— OG7
C4B63_38g42 ⚠
tRNA nucleotidyltransferase
— OG7
C4B63_70g101 ⚠
conserved hypothetical protein
— OG7
C4B63_2g362 ⚠
conserved hypothetical protein
— OG7
C4B63_294g18 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_49g130 ⚠
Putative hydrolase C777.06c
— OG7
C4B63_42g192 ⚠
N-alpha-acetyltransferase 25, NatB auxiliary
— OG7
C4B63_24g224 ⚠
conserved hypothetical protein
— OG7
C4B63_49g131 ⚠
conserved hypothetical protein
— OG7
C4B63_160g33 ⚠
ubiquitin-activating enzyme E1
— OG7
C4B63_24g246 ⚠
kynureninase
— OG7
C4B63_30g290 ⚠
mercaptopyruvate sulfurtransferase
— OG7
C4B63_212g12 ⚠
anion-transporting ATPase-like
— OG7
C4B63_21g280 ⚠
ribonuclease mar1
— OG7
Page 1 of 2
Next →
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.