C4B63_148g30

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_128061 OG7: OG7_0028967 96 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 96 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_11g22 ⚠
RNA pseudouridylate synthase
— OG6
C4B63_6g521 ⚠
DIS3-like exonuclease
— OG7
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_14g216 ⚠
conserved hypothetical protein
— Both
C4B63_2g388 ⚠
conserved hypothetical protein
— Both
C4B63_40g159 ⚠
translation initiation factor 2 subunit
— Both
C4B63_21g76 ⚠
Adenosine deaminase-like protein
— Both
C4B63_9g293 ⚠
Mitochondrial-processing peptidase subunit al
— Both
C4B63_32g322 ⚠
protein kinase
— Both
C4B63_187g34 ⚠
protein kinase
— Both
C4B63_187g35 ⚠
protein kinase
— Both
C4B63_18g280 ⚠
conserved hypothetical protein
— OG7
C4B63_18g25 ⚠
RNA pseudouridylate synthase domain-containin
— Both
C4B63_18g64 ⚠
RNA pseudouridylate synthase
— OG6
C4B63_18g142 ⚠
conserved hypothetical protein
— Both
C4B63_51g96 ⚠
UPF0301 protein BT 1078
— Both
C4B63_144g28 ⚠
conserved hypothetical protein
— Both
C4B63_69g59 ⚠
conserved hypothetical protein
— Both
C4B63_6g113 ⚠
ribonucleoside-diphosphate reductase large ch
— Both
C4B63_212g12 ⚠
anion-transporting ATPase-like
— Both
C4B63_12g179 ⚠
anion-transporting ATPase-like
— Both
C4B63_70g101 ⚠
conserved hypothetical protein
— Both
C4B63_9g323 ⚠
conserved hypothetical protein
— Both
C4B63_70g82 ⚠
protein kinase
— OG7
C4B63_10g137 ⚠
conserved hypothetical protein
— OG7
C4B63_263g16 ⚠
Programmed cell death protein 2-like
— OG7
C4B63_7g324 ⚠
Programmed cell death protein 2, C-terminal d
— OG7
C4B63_2g75 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_2g352 ⚠
nucleolar GTP-binding protein 1(fragment)
— OG7
C4B63_2g828 ⚠
ankyrin repeat protein
— OG7
C4B63_2g74 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_4g272 ⚠
cholinephosphate cytidylyltransferase A
— OG7
C4B63_7g323 ⚠
conserved hypothetical protein
— OG7
C4B63_4g244 ⚠
ankyrin repeat family protein
— OG7
C4B63_56g58 ⚠
ankyrin,
— OG7
C4B63_4g141 ⚠
syntaxin 5
— Both
C4B63_2g41 ⚠
Protein kinase domain
— OG7
C4B63_70g84 ⚠
serine/threonine protein kinase
— OG7
C4B63_301g7 ⚠
conserved hypothetical protein
— OG7
C4B63_63g31 ⚠
Carboxy-terminal domain RNA polymerase II pol
— OG7
C4B63_23g189 ⚠
Uncharacterized protein C2F7.02c
— OG7
C4B63_48g7 ⚠
NLI interacting factor-like phosphatase
— OG7
C4B63_11g24 ⚠
TFIIF-stimulated CTD phosphatase
— OG7
C4B63_2g833 ⚠
Probable C-terminal domain small phosphatase
— OG7
C4B63_54g5 ⚠
TFIIF-stimulated CTD phosphatase
— OG7
C4B63_95g34 ⚠
mitochondrial processing peptidase alpha subu
— OG7
C4B63_58g112 ⚠
mitochondrial processing peptidase alpha subu
— OG7
C4B63_20g3 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_16g30 ⚠
poly(A)-specific ribonuclease PARN
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.