C4B63_95g34

mitochondrial processing peptidase alpha subunit
Trypanosoma cruzi Dm28c 2018 OG6: OG6_146937 OG7: OG7_0001887 105 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 105 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_63g95 ⚠
poly(A)-specific ribonuclease PARN
— OG7
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
C4B63_2g828 ⚠
ankyrin repeat protein
— OG7
C4B63_19g271 ⚠
conserved hypothetical protein
— OG7
C4B63_20g11 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_20g10 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_2g352 ⚠
nucleolar GTP-binding protein 1(fragment)
— OG7
C4B63_17g239 ⚠
conserved hypothetical protein
— OG7
C4B63_44g214 ⚠
conserved hypothetical protein
— OG7
C4B63_17g71 ⚠
cholinephosphate cytidylyltransferase A
— OG7
C4B63_7g165 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_51g96 ⚠
UPF0301 protein BT 1078
— OG7
C4B63_11g71 ⚠
conserved hypothetical protein
— OG7
C4B63_37g366 ⚠
thimet oligopeptidase
— OG7
C4B63_2g75 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_70g572c ⚠
cytochrome b5
— OG7
C4B63_42g180 ⚠
nitrate reductase
— OG7
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_28g47 ⚠
Serine/threonine-protein phosphatase 4 regula
— OG7
C4B63_168g23 ⚠
Programmed cell death protein 2, C-terminal d
— OG7
C4B63_16g30 ⚠
poly(A)-specific ribonuclease PARN
— OG7
C4B63_7g236 ⚠
regulatory subunit of protein kinase a-like p
— OG7
C4B63_7g324 ⚠
Programmed cell death protein 2, C-terminal d
— OG7
C4B63_7g173 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_7g169 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_7g161 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_2g785 ⚠
conserved hypothetical protein
— OG7
C4B63_24g246 ⚠
kynureninase
— OG7
C4B63_17g127 ⚠
Desumoylating isopeptidase 1
— OG7
C4B63_13g41 ⚠
protein kinase
— OG7
C4B63_6g391 ⚠
protein kinase
— OG7
C4B63_54g35 ⚠
protein kinase
— OG7
C4B63_13g231 ⚠
serine/threonine protein kinase
— OG7
C4B63_23g122 ⚠
serine/threonine protein kinase
— OG7
C4B63_45g139 ⚠
serine/threonine protein kinase
— OG7
C4B63_4g180 ⚠
serine/threonine protein kinase
— OG7
C4B63_58g54 ⚠
serine/threonine protein kinase
— OG7
C4B63_186g6 ⚠
Desumoylating isopeptidase 1
— OG7
C4B63_9g323 ⚠
conserved hypothetical protein
— OG7
C4B63_212g12 ⚠
anion-transporting ATPase-like
— OG7
C4B63_297g16 ⚠
cholinephosphate cytidylyltransferase A
— OG7
C4B63_20g6 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_10g403 ⚠
cytochrome b5
— OG7
C4B63_2g419 ⚠
UDP-galactose 4-epimerase
— OG7
C4B63_148g30 ⚠
conserved hypothetical protein
— OG7
C4B63_87g16 ⚠
pitrilysin-like metalloprotease
— OG7
C4B63_30g290 ⚠
mercaptopyruvate sulfurtransferase
— OG7
C4B63_18g286 ⚠
conserved hypothetical protein
— OG7
C4B63_348g23 ⚠
cytochrome b5
— OG7
C4B63_102g71 ⚠
Programmed cell death protein 2, C-terminal d
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.