C4B63_20g11

D-isomer specific 2-hydroxyacid dehydrogenase-protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_103299 OG7: OG7_0001275 87 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 87 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_81g53 ⚠
GTP-binding protein(fragment)
— Both
C4B63_2g785 ⚠
conserved hypothetical protein
— Both
C4B63_10g125 ⚠
ankyrin
— Both
C4B63_63g95 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_16g30 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_160g6 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_114g23 ⚠
UBX domain-containing protein 3
— +2 more Both
C4B63_183g15 ⚠
spermidine synthase
— Both
C4B63_38g147 ⚠
spermidine synthase
— Both
C4B63_38g167 ⚠
spermidine synthase
— Both
C4B63_9g293 ⚠
Mitochondrial-processing peptidase subunit al
— Both
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_4g356 ⚠
RNA-binding protein 29
— Both
C4B63_51g96 ⚠
UPF0301 protein BT 1078
— Both
C4B63_48g163 ⚠
ARF-like 2 binding protein BART
— Both
C4B63_87g16 ⚠
pitrilysin-like metalloprotease
— Both
C4B63_87g17 ⚠
pitrilysin-like metalloprotease
— Both
C4B63_212g12 ⚠
anion-transporting ATPase-like
— Both
C4B63_12g179 ⚠
anion-transporting ATPase-like
— Both
C4B63_70g101 ⚠
conserved hypothetical protein
— Both
C4B63_32g236 ⚠
transketolase
— +2 more Both
C4B63_9g323 ⚠
conserved hypothetical protein
— Both
C4B63_263g16 ⚠
Programmed cell death protein 2-like
— OG7
C4B63_4g244 ⚠
ankyrin repeat family protein
— OG7
C4B63_56g58 ⚠
ankyrin,
— OG7
C4B63_2g828 ⚠
ankyrin repeat protein
— OG7
C4B63_107g3 ⚠
Putative methyltransferase NSUN6
— OG7
C4B63_11g99 ⚠
Putative methyltransferase NSUN6
— OG7
C4B63_7g147 ⚠
Tetratricopeptide repeat protein 39C
— OG7
C4B63_23g124 ⚠
NOL1/NOP2/sun family
— OG7
C4B63_44g246 ⚠
nucleolar protein
— OG7
C4B63_6g420 ⚠
Probable 28S rRNA (cytosine-C(5))-methyltrans
— OG7
C4B63_24g215 ⚠
methyltransferase domain containing protein
— OG7
C4B63_16g17 ⚠
acetyl-CoA synthetase
— Both
C4B63_7g324 ⚠
Programmed cell death protein 2, C-terminal d
— OG7
C4B63_7g323 ⚠
conserved hypothetical protein
— OG7
C4B63_2g75 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_2g74 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_95g34 ⚠
mitochondrial processing peptidase alpha subu
— OG7
C4B63_58g112 ⚠
mitochondrial processing peptidase alpha subu
— OG7
C4B63_2g352 ⚠
nucleolar GTP-binding protein 1(fragment)
— OG7
C4B63_4g272 ⚠
cholinephosphate cytidylyltransferase A
— OG7
C4B63_6g521 ⚠
DIS3-like exonuclease
— OG7
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_8g510 ⚠
conserved hypothetical protein
— Both
C4B63_47g72 ⚠
enolase
— +2 more Both
C4B63_23g212 ⚠
serine/threonine-protein kinase
— OG6
C4B63_7g165 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— +2 more Both
C4B63_20g10 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— +2 more Both
C4B63_7g157 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— +2 more Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.