C4B63_7g147

Tetratricopeptide repeat protein 39C
Trypanosoma cruzi Dm28c 2018 OG6: OG6_103751 OG7: OG7_0003879 46 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 46 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_7g165 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_157g19 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_171g22 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_6g269 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_513g4 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_330g12 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_16g17 ⚠
acetyl-CoA synthetase
— OG7
C4B63_351g6 ⚠
conserved hypothetical protein
— OG7
C4B63_22g169 ⚠
conserved hypothetical protein
— OG7
C4B63_4g184 ⚠
citrate synthase
— OG7
C4B63_20g11 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_20g10 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_2g551 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
C4B63_20g3 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_20g1 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_7g157 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_7g173 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_7g169 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_7g161 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_20g6 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_24g215 ⚠
methyltransferase domain containing protein
— OG7
C4B63_10g103 ⚠
Hercynine oxygenase
— OG7
C4B63_25g305 ⚠
conserved hypothetical protein
— OG7
C4B63_107g3 ⚠
Putative methyltransferase NSUN6
— OG7
C4B63_9g484 ⚠
5-methylcytosine rRNA methyltransferase NSUN4
— OG7
C4B63_54g53 ⚠
conserved hypothetical protein
— OG7
C4B63_6g420 ⚠
Probable 28S rRNA (cytosine-C(5))-methyltrans
— OG7
C4B63_286g21 ⚠
conserved hypothetical protein
— OG7
C4B63_210g33 ⚠
p-nitrophenylphosphatase
— OG7
C4B63_44g246 ⚠
nucleolar protein
— OG7
C4B63_23g124 ⚠
NOL1/NOP2/sun family
— OG7
C4B63_54g54 ⚠
Small subunit processome component 20 homolog
— OG7
C4B63_63g10 ⚠
conserved hypothetical protein
— OG7
C4B63_210g32 ⚠
p-nitrophenylphosphatase
— OG7
C4B63_11g99 ⚠
Putative methyltransferase NSUN6
— OG7
C4B63_200g30 ⚠
p-nitrophenylphosphatase
— OG7
C4B63_4g338 ⚠
conserved hypothetical protein
— OG7
C4B63_4g339 ⚠
conserved hypothetical protein
— OG7
C4B63_80g25 ⚠
ubiquitin hydrolase
— OG7
C4B63_85g61 ⚠
conserved hypothetical protein
— OG7
C4B63_2g83 ⚠
ubiquitin hydrolase
— OG7
C4B63_2g502 ⚠
ubiquitin carboxyl-terminal hydrolase
— OG7
C4B63_252g9 ⚠
ubiquitin carboxyl-terminal hydrolase
— OG7
C4B63_4g577 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_42g205 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_42g204 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.