C4B63_63g10

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_146958 OG7: OG7_0037735 102 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 102 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_83g68 ⚠
protein phosphatase 2C
— OG6
C4B63_2g700 ⚠
conserved hypothetical protein
— Both
C4B63_94g50 ⚠
myosin heavy chain
— OG6
C4B63_47g94 ⚠
Myosin motor domain superfamily protein
— OG6
C4B63_1g39 ⚠
paraflagellar rod component
— Both
C4B63_30g117 ⚠
Unconventional myosin
— OG6
C4B63_224g33 ⚠
conserved hypothetical protein
— Both
C4B63_21g237 ⚠
myosin heavy chain
— OG6
C4B63_18g180 ⚠
Tetratricopeptide repeat protein 39B
— Both
C4B63_76g57 ⚠
Tripartite attachment complex protein 102
— Both
C4B63_41g196 ⚠
General transcription factor 3C polypeptide 3
— Both
C4B63_76g58 ⚠
Tripartite attachment complex protein 102
— Both
C4B63_4g184 ⚠
citrate synthase
— Both
C4B63_71g164 ⚠
mucin TcMUCII
— OG6
C4B63_71g5 ⚠
mucin TcMUCII
— OG6
C4B63_71g85 ⚠
mucin TcMUCII
— OG6
C4B63_386g19 ⚠
mucin TcMUCII
— OG6
C4B63_37g159 ⚠
mucin TcMUCII
— OG6
C4B63_52g168 ⚠
Cilia- and flagella-associated protein 44
— Both
C4B63_39g160 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_63g7 ⚠
eukaryotic translation initiation factor 3 su
— Both
C4B63_286g18 ⚠
eukaryotic translation initiation factor 3 su
— Both
C4B63_293g4 ⚠
I/6 autoantigen
— Both
C4B63_49g56 ⚠
I/6 autoantigen
— Both
C4B63_7g312 ⚠
conserved hypothetical protein
— Both
C4B63_263g1 ⚠
conserved hypothetical protein
— Both
C4B63_7g57 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_24g215 ⚠
methyltransferase domain containing protein
— OG7
C4B63_107g3 ⚠
Putative methyltransferase NSUN6
— OG7
C4B63_11g99 ⚠
Putative methyltransferase NSUN6
— OG7
C4B63_23g124 ⚠
NOL1/NOP2/sun family
— OG7
C4B63_6g420 ⚠
Probable 28S rRNA (cytosine-C(5))-methyltrans
— OG7
C4B63_44g246 ⚠
nucleolar protein
— OG7
C4B63_54g50 ⚠
conserved hypothetical protein
— OG7
C4B63_11g90 ⚠
conserved hypothetical protein
— OG7
C4B63_4g502 ⚠
ABC transporter
— OG7
C4B63_113g34 ⚠
ABC transporter
— OG7
C4B63_122g17 ⚠
conserved hypothetical protein
— OG7
C4B63_87g20 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_7g147 ⚠
Tetratricopeptide repeat protein 39C
— OG7
C4B63_263g3 ⚠
conserved hypothetical protein
— Both
C4B63_24g272 ⚠
Zn-finger in Ran binding protein and others/S
— Both
C4B63_24g273 ⚠
Probable E3 ubiquitin-protein ligase HERC1
— Both
C4B63_11g83 ⚠
Eukaryotic translation initiation factor 3 su
— Both
C4B63_6g490 ⚠
Vacuole membrane protein 1
— Both
C4B63_81g14 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_87g21 ⚠
conserved hypothetical protein
— OG7
C4B63_7g55 ⚠
conserved hypothetical protein
— OG7
C4B63_4g200 ⚠
conserved hypothetical protein
— Both
C4B63_7g56 ⚠
Protein transport protein sec71
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.