C4B63_2g700

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_139723 OG7: OG7_0043931 98 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 98 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_12g396 ⚠
proteasome alpha 7 subunit
— +1 more Both
C4B63_6g490
Vacuole membrane protein 1
— Both
C4B63_20g172
chaperonin alpha subunit
— OG6
C4B63_21g237 ⚠
myosin heavy chain
— OG6
C4B63_30g117 ⚠
Unconventional myosin
— OG6
C4B63_47g94 ⚠
Myosin motor domain superfamily protein
— OG6
C4B63_94g50 ⚠
myosin heavy chain
— OG6
C4B63_14g199 ⚠
myosin heavy chain
— OG6
C4B63_31g47 ⚠
myosin heavy chain MYA2-related
— OG6
C4B63_80g4 ⚠
Unconventional myosin
— OG6
C4B63_112g35 ⚠
Unconventional myosin
— OG6
C4B63_83g68
protein phosphatase 2C
— OG6
C4B63_2g302 ⚠
proteasome alpha 1 subunit
— +1 more Both
C4B63_70g80 ⚠
proteasome alpha 7 subunit
— +1 more Both
C4B63_2g485 ⚠
T-complex protein 1, beta subunit
— OG6
C4B63_252g22 ⚠
T-complex protein 1, beta subunit
— OG6
C4B63_192g3 ⚠
AAA ATPase
— OG6
C4B63_48g168 ⚠
AAA ATPase
— OG6
C4B63_46g11 ⚠
chaperonin TCP20
— OG6
C4B63_63g10 ⚠
conserved hypothetical protein
— Both
C4B63_162g33 ⚠
chaperonin TCP20
— OG6
C4B63_286g21 ⚠
conserved hypothetical protein
— Both
C4B63_233g5 ⚠
Proteasomal ubiquitin receptor ADRM1
— Both
C4B63_35g173
proteasome 26S non-ATPase subunit 9
— Both
C4B63_16g108 ⚠
chaperonin/T-complex protein 1 gamma subunit
— OG6
C4B63_168g31 ⚠
dynein arm light chain
— OG7
C4B63_2g54 ⚠
conserved hypothetical protein
— OG7
C4B63_13g154 ⚠
elongation factor 2
— OG7
C4B63_13g155 ⚠
elongation factor 2
— OG7
C4B63_13g156 ⚠
elongation factor 2
— OG7
C4B63_11g17 ⚠
translation elongation factor EF-2
— OG7
C4B63_11g18 ⚠
translation elongation factor EF-2
— OG7
C4B63_13g153 ⚠
elongation factor 2
— OG7
C4B63_13g157 ⚠
elongation factor 2
— OG7
C4B63_13g152 ⚠
elongation factor 2
— OG7
C4B63_8g48 ⚠
dynein arm light chain
— OG7
C4B63_13g297 ⚠
Axonemal inner arm dynein light chain
— OG7
C4B63_17g90 ⚠
T-complex protein 1, beta subunit
— OG6
C4B63_102g78 ⚠
dynein arm light chain
— OG7
C4B63_204g23 ⚠
Axonemal inner arm dynein light chain
— OG7
C4B63_4g502 ⚠
ABC transporter
— OG7
C4B63_113g34 ⚠
ABC transporter
— OG7
C4B63_57g111 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
C4B63_6g98 ⚠
RNA polymerase I
— OG7
C4B63_25g312 ⚠
proteasome alpha 3 subunit
— OG7
C4B63_43g129 ⚠
proteasome subunit alpha type-5
— OG7
C4B63_8g530 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
C4B63_48g135 ⚠
proteasome subunit alpha type-1
— OG7
C4B63_22g288
Midasin
— OG7
C4B63_28g104
conserved hypothetical protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.