C4B63_6g98

RNA polymerase I
Trypanosoma cruzi Dm28c 2018 OG6: OG6_139718 OG7: OG7_0019075 123 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 123 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_2g502 ⚠
ubiquitin carboxyl-terminal hydrolase
— OG7
C4B63_13g154 ⚠
elongation factor 2
— OG7
C4B63_9g471 ⚠
ATP-dependent protease binding subunit(fragme
— OG7
C4B63_9g416 ⚠
ATP-dependent Clp protease subunit, heat shoc
— OG7
C4B63_4g103 ⚠
intraflagellar transport protein 140
— OG7
C4B63_281g16 ⚠
intraflagellar transport protein 88
— OG7
C4B63_32g16 ⚠
conserved hypothetical protein
— OG7
C4B63_181g2 ⚠
conserved hypothetical protein
— OG7
C4B63_181g1 ⚠
conserved hypothetical protein
— OG7
C4B63_19g23 ⚠
intraflagellar transport protein 88
— OG7
C4B63_79g90 ⚠
conserved hypothetical protein
— OG7
C4B63_13g205 ⚠
RNA editing complex protein MP18
— OG7
C4B63_2g782 ⚠
ATP-dependent RNA helicase
— OG7
C4B63_230g25 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
C4B63_94g58 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_81g40 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_4g90 ⚠
ATP-dependent RNA helicase HEL67
— OG7
C4B63_31g58 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_207g22 ⚠
ATP-dependent RNA helicase HEL67
— OG7
C4B63_21g245 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_6g384 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
C4B63_45g221 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_4g201 ⚠
Protein ILITYHIA
— OG7
C4B63_26g232 ⚠
ubiquitin hydrolase(fragment)
— OG7
C4B63_80g25 ⚠
ubiquitin hydrolase
— OG7
C4B63_2g4 ⚠
ubiquitin hydrolase
— OG7
C4B63_7g391 ⚠
ubiquitin hydrolase
— OG7
C4B63_2g83 ⚠
ubiquitin hydrolase
— OG7
C4B63_26g231 ⚠
ubiquitin hydrolase(fragment)
— OG7
C4B63_4g200 ⚠
conserved hypothetical protein
— OG7
C4B63_7g392 ⚠
ubiquitin hydrolase
— OG7
C4B63_81g17 ⚠
DNA mismatch repair protein MSH2(fragment)
— OG7
C4B63_17g251 ⚠
coatomer subunit epsilon
— OG7
C4B63_23g186 ⚠
aspartyl aminopeptidase
— OG7
C4B63_6g506 ⚠
conserved hypothetical protein
— OG7
C4B63_233g5 ⚠
Proteasomal ubiquitin receptor ADRM1
— OG7
C4B63_2g54 ⚠
conserved hypothetical protein
— OG7
C4B63_6g119 ⚠
oxidoreductase-like protein
— OG7
C4B63_93g66 ⚠
conserved hypothetical protein
— OG7
C4B63_9g220 ⚠
Thioredoxin domain-containing protein PLP3A
— OG7
C4B63_80g17 ⚠
ATP binding protein-like protein
— OG7
C4B63_62g90 ⚠
ribosome biogenesis protein
— OG7
C4B63_37g373 ⚠
ribosome biogenesis protein
— OG7
C4B63_69g26 ⚠
endo-beta-N-acetylglucosaminidase
— OG7
C4B63_49g82 ⚠
conserved hypothetical protein
— OG7
C4B63_30g226 ⚠
lipin
— OG7
C4B63_30g227 ⚠
lipin
— OG7
C4B63_17g253 ⚠
Paraflagellar Rod Proteome Component 9
— OG7
C4B63_63g14 ⚠
RNA editing complex protein MP63
— OG7
C4B63_52g137 ⚠
conserved hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.