C4B63_81g40

ATP-dependent DEAD/H RNA helicase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100364 OG7: OG7_0000120 82 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 82 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_42g593c ⚠
small nuclear ribonucleoprotein Sm-E
— OG7
C4B63_69g174c ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
C4B63_144g102c ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
C4B63_271g80c ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
C4B63_43g1065c ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
C4B63_2g1123c ⚠
small nuclear ribonucleoprotein Sm-F
— OG7
C4B63_11g283c ⚠
U6 snRNA-associated Sm-like protein LSm8
— OG7
C4B63_40g163 ⚠
leucine-rich repeat protein (LRRP)
— OG7
C4B63_17g50 ⚠
Outer row dynein-assembly protein 7
— OG7
C4B63_34g305 ⚠
Kinetoplastid RNA editing protein 1
— OG7
C4B63_57g111 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
C4B63_59g114 ⚠
conserved hypothetical protein
— OG7
C4B63_17g180c ⚠
U6 snRNA-associated Sm-like protein LSm4
— OG7
C4B63_528g4 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
C4B63_34g306 ⚠
Kinetoplastid RNA editing protein 1(fragment)
— OG7
C4B63_133g31 ⚠
U5 snRNP-specific 40 kDa protein
— OG7
C4B63_78g39 ⚠
RNA-editing complex protein
— OG7
C4B63_19g190 ⚠
MP44
— OG7
C4B63_6g98 ⚠
RNA polymerase I
— OG7
C4B63_49g685c ⚠
small nuclear ribonucleoprotein
— OG7
C4B63_85g62 ⚠
KREL1
— OG7
C4B63_93g67 ⚠
RNA editing ligase
— OG7
C4B63_528g3 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
C4B63_40g18 ⚠
2-oxoglutarate dehydrogenase E1 component
— OG7
C4B63_2g427 ⚠
Nucleoporin
— OG7
C4B63_39g319 ⚠
60S ribosomal protein L10a
— OG7
C4B63_4g178 ⚠
60S ribosomal protein L10a
— OG7
C4B63_45g133 ⚠
splicing factor TSR1
— OG7
C4B63_4g427 ⚠
RNA-binding protein
— OG7
C4B63_13g277 ⚠
N-acetyltransferase subunit Nat1
— OG7
C4B63_132g76 ⚠
60S ribosomal protein L10a
— OG7
C4B63_25g237 ⚠
eukaryotic translation initiation factor 3 su
— OG7
C4B63_204g13 ⚠
N-acetyltransferase subunit Nat1
— OG7
C4B63_4g429 ⚠
RNA-binding protein
— OG7
C4B63_528g2 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
C4B63_19g275 ⚠
2-oxoglutarate dehydrogenase subunit
— OG7
C4B63_179g1 ⚠
2-oxoglutarate dehydrogenase E1 component(fra
— OG7
C4B63_179g2 ⚠
2-oxoglutarate dehydrogenase subunit
— OG7
C4B63_2g383 ⚠
RNA editing complex protein MP46
— OG7
C4B63_138g26 ⚠
translation-associated element 2
— OG7
C4B63_292g17 ⚠
translation-associated element 2
— OG7
C4B63_292g16 ⚠
translation-associated element 2
— OG7
C4B63_13g204 ⚠
MP24
— OG7
C4B63_63g14 ⚠
RNA editing complex protein MP63
— OG7
C4B63_8g58 ⚠
Dynein assembly factor 1, axonemal homolog
— OG7
C4B63_271g10 ⚠
conserved hypothetical protein
— OG7
C4B63_12g2035c ⚠
zinc-finger protein 2
— OG7
C4B63_18g169 ⚠
Zinc finger CCCH domain-containing protein 47
— OG7
C4B63_397g11 ⚠
zinc-finger CCCH domain containing protein 11
— OG7
C4B63_43g202 ⚠
hook complex protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.