C4B63_4g429

RNA-binding protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_157061 OG7: OG7_0028950 60 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 60 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_93g76 ⚠
40S ribosomal protein S11
— OG7
C4B63_54g39 ⚠
phosphatidylinositol-4-phosphate 5-kinase-lik
— OG7
C4B63_86g237c ⚠
lipoic acid containing carrier protein
— OG7
C4B63_8g463 ⚠
conserved hypothetical protein
— OG7
C4B63_10g159 ⚠
hypothetical Zinc-finger containing protein
— OG7
C4B63_58g44 ⚠
Major Facilitator Superfamily
— OG7
C4B63_13g129 ⚠
phosphatidylinositol-4-phosphate 5-kinase
— OG7
C4B63_22g262c ⚠
DNA-directed RNA polymerase 2, RPB12 subunit
— OG7
C4B63_6g571 ⚠
conserved hypothetical protein
— OG7
C4B63_12g216 ⚠
40S ribosomal protein S5
— OG7
C4B63_12g217 ⚠
40S ribosomal protein S5
— OG7
C4B63_46g87 ⚠
conserved hypothetical protein
— OG7
C4B63_38g75 ⚠
conserved hypothetical protein
— OG7
C4B63_43g163 ⚠
40S ribosomal protein S11
— OG7
C4B63_2g691 ⚠
30S Ribosomal protein S17
— OG7
C4B63_7g265 ⚠
phosphatidylinositol phosphate kinase alpha
— OG7
C4B63_7g426 ⚠
Double RNA binding domain protein 7
— OG7
C4B63_58g125 ⚠
conserved hypothetical protein
— OG7
C4B63_230g25 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
C4B63_94g58 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_81g40 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_4g90 ⚠
ATP-dependent RNA helicase HEL67
— OG7
C4B63_31g58 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_207g22 ⚠
ATP-dependent RNA helicase HEL67
— OG7
C4B63_21g245 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_6g384 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
C4B63_45g221 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_51g192 ⚠
protein kinase A regulatory subunit
— OG7
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
C4B63_7g236 ⚠
regulatory subunit of protein kinase a-like p
— OG7
C4B63_25g237 ⚠
eukaryotic translation initiation factor 3 su
— Both
C4B63_7g223
eukaryotic translation initiation factor 3 su
— OG6
C4B63_42g186 ⚠
spliceosome-associated protein
— Both
C4B63_179g1 ⚠
2-oxoglutarate dehydrogenase E1 component(fra
— Both
C4B63_179g2 ⚠
2-oxoglutarate dehydrogenase subunit
— Both
C4B63_19g275 ⚠
2-oxoglutarate dehydrogenase subunit
— Both
C4B63_11g281 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_40g18 ⚠
2-oxoglutarate dehydrogenase E1 component
— Both
C4B63_4g427 ⚠
RNA-binding protein
— Both
C4B63_45g126
RNA recognition motif (a.k.a. RRM, RBD, or RN
— OG6
C4B63_45g133 ⚠
splicing factor TSR1
— Both
C4B63_4g178 ⚠
60S ribosomal protein L10a
— Both
C4B63_39g319 ⚠
60S ribosomal protein L10a
— Both
C4B63_204g13 ⚠
N-acetyltransferase subunit Nat1
— Both
C4B63_4g172 ⚠
RNA-binding protein
— Both
C4B63_10g167 ⚠
conserved hypothetical protein
— Both
C4B63_132g76 ⚠
60S ribosomal protein L10a
— Both
C4B63_13g277 ⚠
N-acetyltransferase subunit Nat1
— Both
C4B63_4g347 ⚠
conserved hypothetical protein
— Both
C4B63_47g55 ⚠
eukaryotic translation initiation factor 5
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.