C4B63_42g593c

small nuclear ribonucleoprotein Sm-E
Trypanosoma cruzi Dm28c 2018 OG6: OG6_102613 OG7: OG7_0001217 143 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 143 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_11g283c ⚠
U6 snRNA-associated Sm-like protein LSm8
— +2 more OG7
C4B63_2g782 ⚠
ATP-dependent RNA helicase
— Both
C4B63_43g1065c ⚠
U6 snRNA-associated Sm-like protein LSm7p
— +2 more OG7
C4B63_271g80c ⚠
U6 snRNA-associated Sm-like protein LSm7p
— +2 more OG7
C4B63_2g1123c ⚠
small nuclear ribonucleoprotein Sm-F
— +4 more Both
C4B63_45g221 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_69g174c ⚠
U6 snRNA-associated Sm-like protein LSm6p
— +2 more OG7
C4B63_6g384 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
C4B63_144g102c ⚠
U6 snRNA-associated Sm-like protein LSm6p
— +2 more OG7
C4B63_207g22 ⚠
ATP-dependent RNA helicase HEL67
— OG7
C4B63_31g58 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_4g90 ⚠
ATP-dependent RNA helicase HEL67
— OG7
C4B63_81g40 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_94g58 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_230g25 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
C4B63_21g245 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_2g297 ⚠
conserved hypothetical protein
— OG7
C4B63_13g155 ⚠
elongation factor 2
— OG7
C4B63_13g154 ⚠
elongation factor 2
— OG7
C4B63_2g154 ⚠
PRP8 protein homologue
— OG7
C4B63_137g45 ⚠
receptor for activated C kinase 1
— OG7
C4B63_43g214 ⚠
U4/U6 small nuclear ribonuclear protein
— OG7
C4B63_17g179 ⚠
Importin subunit beta-3
— OG7
C4B63_22g108 ⚠
Replication Factor C Subunit 1-related protei
— OG7
C4B63_4g258 ⚠
prolyl-tRNA synthetase
— OG7
C4B63_2g762 ⚠
replication factor C, subunit 3
— OG7
C4B63_61g82 ⚠
Chromosome transmission fidelity protein 18 h
— OG7
C4B63_28g129 ⚠
replication factor C, subunit 1
— OG7
C4B63_18g277 ⚠
replication factor C, subunit 2
— OG7
C4B63_61g81 ⚠
conserved hypothetical protein
— OG7
C4B63_63g41 ⚠
replication factor C, subunit 3
— OG7
C4B63_39g340 ⚠
replication factor C, subunit 4
— OG7
C4B63_4g269 ⚠
conserved hypothetical protein
— OG7
C4B63_13g162 ⚠
cap guanine-N7 methyltransferase
— OG7
C4B63_83g29 ⚠
ATP-dependent protease ATPase subunit HslU1
— OG7
C4B63_31g66 ⚠
conserved hypothetical protein
— OG7
C4B63_76g32 ⚠
guide RNA associated protein, GAP2
— OG7
C4B63_95g32 ⚠
conserved hypothetical protein
— OG7
C4B63_42g42 ⚠
co-chaperone GrpE
— OG7
C4B63_2g376 ⚠
ribosome assembly protein RRB1
— OG7
C4B63_271g10 ⚠
conserved hypothetical protein
— OG7
C4B63_14g171 ⚠
ubiquitin-protein ligase
— OG7
C4B63_2g815 ⚠
conserved hypothetical protein
— OG7
C4B63_6g517 ⚠
geranylgeranyl transferase type II beta subun
— OG7
C4B63_102g53 ⚠
conserved hypothetical protein
— OG7
C4B63_4g320 ⚠
conserved hypothetical protein
— OG7
C4B63_85g75 ⚠
ubiquitin activating enzyme
— OG7
C4B63_8g54 ⚠
conserved hypothetical protein
— OG7
C4B63_84g82 ⚠
DNA mismatch repair protein MSH2
— OG7
C4B63_31g99 ⚠
WD repeat-containing protein 17
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.