C4B63_76g32

guide RNA associated protein, GAP2
Trypanosoma cruzi Dm28c 2018 OG6: OG6_139815 OG7: OG7_0037740 164 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 164 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_4g320
conserved hypothetical protein
— Both
C4B63_2g376 ⚠
ribosome assembly protein RRB1
— Both
C4B63_4g269
conserved hypothetical protein
— Both
C4B63_271g10 ⚠
conserved hypothetical protein
— OG7
C4B63_43g202 ⚠
hook complex protein, conserved
— OG7
C4B63_4g258
prolyl-tRNA synthetase
— Both
C4B63_22g164 ⚠
calpain-like cysteine peptidase
— OG6
C4B63_21g31 ⚠
conserved hypothetical protein
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_9g450 ⚠
conserved hypothetical protein
— OG6
C4B63_2g799 ⚠
tRNA wybutosine-synthesizing protein 4
— Both
C4B63_11g475
COP9 signalosome complex subunit 2
— Both
C4B63_28g39 ⚠
Putative ankyrin repeat protein RF 0381
— OG6
C4B63_15g18 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_7g347
V-type ATPase, A subunit
— Both
C4B63_4g377 ⚠
Zinc finger protein 474
— Both
C4B63_3g552 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_39g357
ATP synthase
— Both
C4B63_4g378 ⚠
Zinc finger C2HC domain-containing protein 1C
— Both
C4B63_42g221
kinesin
— OG6
C4B63_70g126
conserved hypothetical protein
— Both
C4B63_44g120
conserved hypothetical protein
— Both
C4B63_22g123 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_3g554 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_3g551 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_85g64
DNA-damage inducible protein DDI1-like protei
— Both
C4B63_42g99
E3 ubiquitin-protein ligase HEL2
— Both
C4B63_22g161 ⚠
calpain-like cysteine peptidase
— OG6
C4B63_43g143 ⚠
protein kinase
— Both
C4B63_6g258 ⚠
Vacuolar proton pump subunit B
— Both
C4B63_6g257 ⚠
Vacuolar proton pump subunit B
— Both
C4B63_32g238 ⚠
tubulin folding cofactor D
— Both
C4B63_47g49 ⚠
tRNA pseudouridine synthase 1
— Both
C4B63_227g4 ⚠
Zinc finger protein 474
— Both
C4B63_93g66
conserved hypothetical protein
— Both
C4B63_22g95
conserved hypothetical protein
— Both
C4B63_8g478 ⚠
RNA-editing complex protein MP100
— OG7
C4B63_42g42
co-chaperone GrpE
— OG7
C4B63_14g171 ⚠
ubiquitin-protein ligase
— OG7
C4B63_61g81 ⚠
conserved hypothetical protein
— OG7
C4B63_2g815 ⚠
conserved hypothetical protein
— OG7
C4B63_63g41 ⚠
replication factor C, subunit 3
— OG7
C4B63_144g102c ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
C4B63_2g817 ⚠
conserved hypothetical protein
— OG7
C4B63_8g527 ⚠
pseudouridylate synthase I
— OG7
C4B63_8g540 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
C4B63_133g51
heat shock protein 70
— OG7
C4B63_52g51 ⚠
serine/threonine protein kinase
— OG7
C4B63_25g120 ⚠
Protein kinase domain
— OG7
C4B63_56g88 ⚠
Zinc finger C2HC domain-containing protein 1C
— OG7
Page 1 of 4
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.