C4B63_22g288

Midasin
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100908 OG7: OG7_0004933 149 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 149 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_4g103
intraflagellar transport protein 140
— OG7
C4B63_8g48 ⚠
dynein arm light chain
— OG7
C4B63_204g23 ⚠
Axonemal inner arm dynein light chain
— OG7
C4B63_102g78 ⚠
dynein arm light chain
— OG7
C4B63_28g113 ⚠
dynein arm light chain
— OG7
C4B63_168g31 ⚠
dynein arm light chain
— OG7
C4B63_13g297 ⚠
Axonemal inner arm dynein light chain
— OG7
C4B63_4g244 ⚠
ankyrin repeat family protein
— OG7
C4B63_4g506 ⚠
Microtubule Associated kinase (CAP-Gly domain
— OG7
C4B63_10g125 ⚠
ankyrin
— OG7
C4B63_11g73 ⚠
conserved hypothetical protein
— OG7
C4B63_11g72 ⚠
conserved hypothetical protein
— OG7
C4B63_4g431
intraflagellar transport protein 52
— OG7
C4B63_12g196
conserved hypothetical protein
— OG7
C4B63_4g531
Cleavage stimulation factor subunit 1
— OG7
C4B63_42g199 ⚠
conserved hypothetical protein
— OG7
C4B63_28g122 ⚠
conserved hypothetical protein
— OG7
C4B63_80g10 ⚠
E3 ubiquitin-protein ligase HECTD3
— OG7
C4B63_19g137 ⚠
cleavage and polyadenylation specificity fact
— OG7
C4B63_80g9 ⚠
conserved hypothetical protein
— OG7
C4B63_43g154 ⚠
TRAF3-interacting protein 1
— OG7
C4B63_42g198 ⚠
conserved hypothetical protein
— OG7
C4B63_43g187 ⚠
structural maintenance of chromosome protein
— OG7
C4B63_9g224 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_9g223 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_127g31 ⚠
Flagellum attachment zone protein 14
— OG7
C4B63_14g249 ⚠
structural maintenance of chromosome 3
— OG7
C4B63_19g83 ⚠
Regulatory-associated protein of TOR1
— OG7
C4B63_16g102 ⚠
conserved hypothetical protein
— OG7
C4B63_16g101 ⚠
conserved hypothetical protein
— OG7
C4B63_42g254
conserved hypothetical protein
— OG7
C4B63_32g248
conserved hypothetical protein
— OG7
C4B63_23g82
conserved hypothetical protein
— OG7
C4B63_17g128 ⚠
cleavage and polyadenylation specificity fact
— OG7
C4B63_11g50
General negative regulator of transcription s
— OG7
C4B63_22g166 ⚠
Regulatory-associated protein of mTOR
— OG7
C4B63_79g36
CCR4-NOT transcription complex subunit 1
— OG7
C4B63_55g168 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_24g195 ⚠
microtubule-associated protein
— OG7
C4B63_24g194 ⚠
microtubule-associated protein
— OG7
C4B63_32g247
conserved hypothetical protein
— OG7
C4B63_31g46 ⚠
structural maintenance of chromosome 3 protei
— OG7
C4B63_80g17 ⚠
ATP binding protein-like protein
— OG7
C4B63_2g54 ⚠
conserved hypothetical protein
— OG7
C4B63_89g51
FYVE zinc-finger containing protein
— OG7
C4B63_38g151 ⚠
tetratricopeptide repeat protein (TPR)
— OG7
C4B63_9g220 ⚠
Thioredoxin domain-containing protein PLP3A
— OG7
C4B63_85g63
Rab-GTPase-TBC domain containing protein
— OG7
C4B63_30g176 ⚠
inorganic polyphosphate/ATP-NAD kinase
— OG7
C4B63_233g5 ⚠
Proteasomal ubiquitin receptor ADRM1
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.