C4B63_19g83

Regulatory-associated protein of TOR1
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101923 OG7: OG7_0005815 99 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 99 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_81g14 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_11g81 ⚠
ribosomal protein L24/L26-like protein
— OG7
C4B63_7g56 ⚠
Protein transport protein sec71
— OG7
C4B63_81g15 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_127g31 ⚠
Flagellum attachment zone protein 14
— OG7
C4B63_9g462 ⚠
U5 snRNP-associated 102 kDa protein
— OG7
C4B63_16g321 ⚠
Rhomboid serine protease/Exocyst complex comp
— OG7
C4B63_42g198 ⚠
conserved hypothetical protein
— OG7
C4B63_87g20 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_7g57 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_87g21 ⚠
conserved hypothetical protein
— OG7
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_7g55 ⚠
conserved hypothetical protein
— OG7
C4B63_22g113 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— OG7
C4B63_42g199 ⚠
conserved hypothetical protein
— OG7
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_7g306 ⚠
cleavage and polyadenylation specificity fact
— OG7
C4B63_83g84 ⚠
conserved hypothetical protein
— OG7
C4B63_25g194 ⚠
conserved hypothetical protein
— OG7
C4B63_31g98 ⚠
Autophagy protein Apg6
— OG7
C4B63_51g88 ⚠
conserved hypothetical protein
— OG7
C4B63_1g57 ⚠
AAA ATPase
— Both
C4B63_28g123 ⚠
conserved hypothetical protein
— Both
C4B63_2g828 ⚠
ankyrin repeat protein
— OG7
C4B63_7g236 ⚠
regulatory subunit of protein kinase a-like p
— OG7
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
C4B63_51g192 ⚠
protein kinase A regulatory subunit
— OG7
C4B63_41g229 ⚠
Flagellum attachment zone protein 2
— OG7
C4B63_30g177 ⚠
condensin complex subunit 2
— OG7
C4B63_143g34 ⚠
condensin complex subunit 2
— OG7
C4B63_143g35 ⚠
conserved hypothetical protein
— OG7
C4B63_30g178 ⚠
conserved hypothetical protein
— OG7
C4B63_23g30 ⚠
conserved hypothetical protein
— OG7
C4B63_22g288 ⚠
Midasin
— OG7
C4B63_10g125 ⚠
ankyrin
— OG7
C4B63_56g58 ⚠
ankyrin,
— OG7
C4B63_28g122 ⚠
conserved hypothetical protein
— Both
C4B63_32g248 ⚠
conserved hypothetical protein
— OG7
C4B63_199g23 ⚠
conserved hypothetical protein
— OG7
C4B63_21g116 ⚠
conserved hypothetical protein
— OG7
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_7g68 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_17g277 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_7g67 ⚠
Sec7 guanine-nucleotide exchange factor
— OG7
C4B63_17g278 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_32g218 ⚠
Trypanosome basal body component protein
— OG7
C4B63_32g219 ⚠
Trypanosome basal body component protein
— OG7
C4B63_55g168 ⚠
Cilia- and flagella-associated protein 57
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.