C4B63_7g306

cleavage and polyadenylation specificity factor
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101260 OG7: OG7_0002417 172 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 172 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_19g137 ⚠
cleavage and polyadenylation specificity fact
— Both
C4B63_23g207 ⚠
tRNA (cytosine(34)-C(5))-methyltransferase
— OG7
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— OG7
C4B63_3g864 ⚠
Mucin-associated surface protein (MASP)
— OG7
C4B63_127g50 ⚠
Protein PPP4R3C
— OG7
C4B63_42g199 ⚠
conserved hypothetical protein
— OG7
C4B63_80g10 ⚠
E3 ubiquitin-protein ligase HECTD3
— OG7
C4B63_80g9 ⚠
conserved hypothetical protein
— OG7
C4B63_42g198 ⚠
conserved hypothetical protein
— OG7
C4B63_9g224 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_9g223 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_127g31 ⚠
Flagellum attachment zone protein 14
— OG7
C4B63_19g83 ⚠
Regulatory-associated protein of TOR1
— OG7
C4B63_42g254 ⚠
conserved hypothetical protein
— OG7
C4B63_23g82 ⚠
conserved hypothetical protein
— OG7
C4B63_17g128 ⚠
cleavage and polyadenylation specificity fact
— OG7
C4B63_22g166 ⚠
Regulatory-associated protein of mTOR
— OG7
C4B63_55g168 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_4g103 ⚠
intraflagellar transport protein 140
— OG7
C4B63_351g1 ⚠
conserved hypothetical protein
— OG7
C4B63_6g418 ⚠
protein kinase
— OG7
C4B63_278g6 ⚠
endosomal trafficking protein RME-8
— OG7
C4B63_18g71 ⚠
cyclosome subunit
— OG7
C4B63_127g30 ⚠
Flagellum attachment zone protein 14
— OG7
C4B63_186g7 ⚠
cleavage and polyadenylation specificity fact
— OG7
C4B63_18g325 ⚠
endosomal trafficking protein RME-8
— OG7
C4B63_18g72 ⚠
cyclosome subunit
— OG7
C4B63_42g216 ⚠
disgorgin
— OG7
C4B63_14g50 ⚠
disgorgin
— OG7
C4B63_14g48 ⚠
rab-like GTPase activating protein
— OG7
C4B63_18g279 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic
— OG7
C4B63_2g798 ⚠
Putative pentatricopeptide repeat-containing
— OG7
C4B63_142g3 ⚠
conserved hypothetical protein
— OG7
C4B63_34g120 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
C4B63_109g39 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
C4B63_238g14 ⚠
conserved hypothetical protein
— OG7
C4B63_114g43 ⚠
conserved hypothetical protein
— OG7
C4B63_42g89 ⚠
importin alpha
— OG7
C4B63_32g248 ⚠
conserved hypothetical protein
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_7g79 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_49g81 ⚠
translation initiation factor IF-2
— OG7
C4B63_49g80 ⚠
translation initiation factor IF-2
— OG7
C4B63_216g37 ⚠
translation initiation factor IF-2
— OG7
C4B63_89g51 ⚠
FYVE zinc-finger containing protein
— OG7
C4B63_28g210 ⚠
translation initiation factor IF-2
— OG7
C4B63_28g211 ⚠
translation initiation factor IF-2
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.