C4B63_19g137

cleavage and polyadenylation specificity factor
Trypanosoma cruzi Dm28c 2018 OG6: OG6_103283 OG7: OG7_0002417 201 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 201 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_7g306 ⚠
cleavage and polyadenylation specificity fact
— Both
C4B63_322g8 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_76g56 ⚠
Aminoacyl tRNA synthase complex-interacting m
— OG7
C4B63_425g4 ⚠
tyrosyl or methionyl-tRNA synthetase
— OG7
C4B63_47g107 ⚠
ABC transporter
— OG7
C4B63_34g372 ⚠
cytochrome b-domain protein
— OG7
C4B63_294g17 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_113g34 ⚠
ABC transporter
— OG7
C4B63_206g11 ⚠
ABC transporter
— OG7
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_30g129 ⚠
rrp44p homologue
— OG7
C4B63_1g57 ⚠
AAA ATPase
— Both
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— Both
C4B63_23g248 ⚠
inorganic pyrophosphatase
— Both
C4B63_14g96 ⚠
isoleucil-tRNA synthetase
— Both
C4B63_28g123 ⚠
conserved hypothetical protein
— Both
C4B63_14g97 ⚠
isoleucyl-tRNA synthetase
— Both
C4B63_28g122 ⚠
conserved hypothetical protein
— Both
C4B63_56g85 ⚠
conserved hypothetical protein
— Both
C4B63_56g84 ⚠
conserved hypothetical protein
— Both
C4B63_34g118 ⚠
conserved hypothetical protein
— Both
C4B63_109g37 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
C4B63_41g200 ⚠
Anaphase-promoting complex subunit 8
— Both
C4B63_6g521 ⚠
DIS3-like exonuclease
— Both
C4B63_49g166 ⚠
alanyl-tRNA synthetase
— Both
C4B63_61g23 ⚠
tRNA-dihydrouridine synthase 3
— Both
C4B63_22g116 ⚠
Pre-mRNA-splicing factor 38
— Both
C4B63_58g37 ⚠
conserved hypothetical protein
— Both
C4B63_355g19 ⚠
inositol-3-phosphate synthase(fragment)
— Both
C4B63_19g179 ⚠
protein kinase
— Both
C4B63_2g244 ⚠
conserved hypothetical protein
— Both
C4B63_21g251 ⚠
conserved hypothetical protein
— Both
C4B63_2g823 ⚠
acyl-CoA dehydrogenase
— Both
C4B63_227g2 ⚠
glucan 1,3-alpha-glucosidase
— Both
C4B63_25g329 ⚠
Nuclear migration protein nudC
— Both
C4B63_52g161 ⚠
tyrosyl-tRNA synthetase
— Both
C4B63_101g36 ⚠
inositol-3-phosphate synthase
— Both
C4B63_124g7 ⚠
Pre-mRNA-splicing factor 38
— Both
C4B63_244g4 ⚠
Nuclear migration protein nudC
— Both
C4B63_49g164 ⚠
alanyl-tRNA synthetase
— Both
C4B63_4g213 ⚠
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
C4B63_4g214 ⚠
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
C4B63_10g517 ⚠
tryptophanyl-tRNA synthetase
— OG6
C4B63_4g375 ⚠
glucan 1,3-alpha-glucosidase
— Both
C4B63_101g15 ⚠
serine peptidase, Clan SC, Family S9B
— Both
C4B63_13g161 ⚠
conserved hypothetical protein
— Both
C4B63_19g195 ⚠
Nuclear pore complex protein 158
— Both
C4B63_49g165 ⚠
alanyl-tRNA synthetase
— Both
C4B63_82g71 ⚠
tryptophanyl-tRNA synthetase
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.