C4B63_82g71

tryptophanyl-tRNA synthetase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101168 OG7: OG7_0005676 120 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 120 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_40g52 ⚠
conserved hypothetical protein
— OG6
C4B63_46g91 ⚠
leucyl-tRNA synthetase
— OG6
C4B63_23g110 ⚠
UDP-glucose:glycoprotein glucosyltransferase
— OG6
C4B63_255g21 ⚠
calreticulin
— OG6
C4B63_28g113 ⚠
dynein arm light chain
— OG6
C4B63_26g266 ⚠
E1-like ubiquitin-activating enzyme
— OG6
C4B63_10g305 ⚠
conserved hypothetical protein
— OG6
C4B63_76g201c ⚠
conserved hypothetical protein
— OG6
C4B63_79g37 ⚠
methionyl-tRNA synthetase
— OG6
C4B63_30g247 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— OG6
C4B63_114g25 ⚠
conserved hypothetical protein
— OG6
C4B63_25g329 ⚠
Nuclear migration protein nudC
— OG6
C4B63_244g4 ⚠
Nuclear migration protein nudC
— OG6
C4B63_25g322 ⚠
U3 small nucleolar RNA-associated protein 25
— OG6
C4B63_18g157 ⚠
DNA ligase I
— OG6
C4B63_124g7 ⚠
Pre-mRNA-splicing factor 38
— OG6
C4B63_22g116 ⚠
Pre-mRNA-splicing factor 38
— OG6
C4B63_18g138 ⚠
UV excision repair RAD23-like protein
— OG6
C4B63_34g120 ⚠
kinetoplast polyadenylation/uridylation facto
— OG6
C4B63_109g39 ⚠
kinetoplast polyadenylation/uridylation facto
— OG6
C4B63_49g81 ⚠
translation initiation factor IF-2
— OG6
C4B63_12g237 ⚠
eukaryotic release factor 3
— OG6
C4B63_11g9 ⚠
eukaryotic translation initiation factor 3 su
— OG6
C4B63_227g2 ⚠
glucan 1,3-alpha-glucosidase
— OG6
C4B63_4g375 ⚠
glucan 1,3-alpha-glucosidase
— OG6
C4B63_23g207 ⚠
tRNA (cytosine(34)-C(5))-methyltransferase
— OG6
C4B63_81g44 ⚠
tRNA (cytosine(34)-C(5))-methyltransferase
— OG6
C4B63_21g251 ⚠
conserved hypothetical protein
— OG6
C4B63_54g28 ⚠
conserved hypothetical protein
— OG6
C4B63_184g38 ⚠
TPR-repeat protein
— OG6
C4B63_13g167 ⚠
stress-inducible protein STI1-like
— OG6
C4B63_109g37 ⚠
Gar1/Naf1 RNA binding region containing prote
— OG6
C4B63_19g113 ⚠
Translation machinery-associated protein 22
— OG6
C4B63_339g3 ⚠
tRNA-dihydrouridine synthase 3
— OG6
C4B63_61g23 ⚠
tRNA-dihydrouridine synthase 3
— OG6
C4B63_149g26 ⚠
GDP-mannose pyrophosphorylase
— OG6
C4B63_83g29 ⚠
ATP-dependent protease ATPase subunit HslU1
— OG6
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— OG6
C4B63_23g248 ⚠
inorganic pyrophosphatase
— OG6
C4B63_14g96 ⚠
isoleucil-tRNA synthetase
— OG6
C4B63_14g97 ⚠
isoleucyl-tRNA synthetase
— OG6
C4B63_12g28 ⚠
RNA-binding protein
— OG6
C4B63_56g85 ⚠
conserved hypothetical protein
— OG6
C4B63_56g84 ⚠
conserved hypothetical protein
— OG6
C4B63_9g247 ⚠
small nuclear ribonucleoprotein protein
— OG6
C4B63_34g118 ⚠
conserved hypothetical protein
— OG6
C4B63_49g165 ⚠
alanyl-tRNA synthetase
— OG6
C4B63_49g164 ⚠
alanyl-tRNA synthetase
— OG6
C4B63_19g137 ⚠
cleavage and polyadenylation specificity fact
— OG6
C4B63_49g166 ⚠
alanyl-tRNA synthetase
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.